Summary
In a multinational study, fasting plasma glucose values in 3583 diabetic patients, aged 34–56 years, were related to the characteristics of these subjects and to the presence and severity of microangiopathy as ascertained by standardised methods. The patients were from nine different populations and ranged in number from 193 to 686 per population (London, Warsaw, Berlin (FRG), New Delhi, Tokyo, Havana, Oklahoma Indians, Arizona Pima Indians, and a national sample in Switzerland). In the total group, mean fasting plasma glucose was 8.1 mmol/l for those on diet alone, 9.7 mmol/l for those on oral agents, and 12.7 mmol/l for insulin-treated patients, of whom 25% had values exceeding 16.5 mmol/l. Since many variables were measured in each patient, it was possible to take into account many confounding factors in evaluating the relationship of plasma glucose levels to retinopathy and nephropathy.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Jarrett RJ, Keen H, Grabauskas AV (1979) The WHO multinational study of vascular disease in diabetes: 1. General description. Diabetes Care 2:175–186
Keen H, Jarrett RJ (1979) The WHO multinational study of vascular disease in diabetes: 2. Macrovascular disease. Diabetes Care 2:187–195
Jarrett RJ, Keen H (1979) The WHO multinational study of vascular disease in diabetes: 3. Microvascular disease. Diabetes Care 2:196–201
Jarrett RJ, Keen H, Grabauskas V, West KM and 20 other collaborators (1980) World Health Organization Multinational Study of Vascular Disease in Diabetes. World Health Organization, Geneva
West KM, Erdreich LJ, Stober JA (1980) Risk factors for retinopathy and nephropathy in diabetes: a detailed study. Diabetes 29: 501–508
Cooper GR (1973) Methods for determining the amount of glucose in blood. CRC Crit Rev Clin Lab Sci 4:101–145
West KM (1978) Measurement of blood glucose. In: Epidemiology of diabetes and its vascular lesions, Elsevier North-Holland, New York, pp 67–68
West KM (1980) Computing and expressing degree of fatness. JAMA 243:1421–1422
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
West, K.M., Ahuja, M.M.S., Bennett, P.H. et al. Interrelationships of microangiopathy, plasma glucose and other risk factors in 3583 diabetic patients: A multinational study. Diabetologia 22, 412–420 (1982). https://doi.org/10.1007/BF00282582
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00282582