Summary
Twenty-one women completed a longitudinal study of glycosylated haemoglobin in normal pregnancy. Glycosylated haemoglobin levels were measured using two independent techniques (ion-exchange column and colorimetric). Concurrent serial oral glucose tolerance tests (75-g glucose load) and erythrocyte indices were obtained. Changes in mean glycosylated haemoglobin were similar with both techniques with a nadir at 17 weeks, a peak at delivery (p<0.002 versus 17 weeks) and a fall post-partum. Glycosylated haemoglobin levels in abnormal pregnancies, e. g. diabetic, should be interpreted in the knowledge of these physiological changes.
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Worth, R., Potter, J.M., Drury, J. et al. Glycosylated haemoglobin in normal pregnancy: a longitudinal study with two independent methods. Diabetologia 28, 76–79 (1985). https://doi.org/10.1007/BF00279919
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DOI: https://doi.org/10.1007/BF00279919