Summary
A new, favism-inducing variant of glucose-6-phosphate dehydrogenase in erythrocytes is described in a Polish family. The enzyme activity has been 0–4% of normal. The enzyme displayed normal heat stability, electrophoretic mobility 105–110% of normal, Km for NADP: 16–22 μM, Km for G-6-P: 26 μM, and the utilization of 2-deoxy-G-6-P: 2–3%.
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Pawlak, A.L., Zagórski, Z., Rozynkowa, D. et al. Polish variant of glucose-6-phosphate dehydrogenase (G-6-PD lublin). Hum Genet 10, 340–343 (1970). https://doi.org/10.1007/BF00278771
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DOI: https://doi.org/10.1007/BF00278771