Summary
In vitro DNA amplification by means of the polymerase chain reaction is currently revolutionizing human molecular genetics. Since its inception in 1985, a wide variety of different methods and their applications in the diagnosis of disease have been described. This review is intended to serve as a brief guide to current and emerging possibilities in this rapidly expanding field.
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Reiss, J., Cooper, D.N. Application of the polymerase chain reaction to the diagnosis of human genetic disease. Hum Genet 85, 1–8 (1990). https://doi.org/10.1007/BF00276316
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DOI: https://doi.org/10.1007/BF00276316