Abstract
Callus and cell suspension cultures of Glycyrrhiza glabra failed to produce detectable amounts of glycyrrhizin, the major oleanane-type triterpene glycoside of the thickening root, or of its 11 —deoxoderivative. However, betulinic acid, a lupane-type triterpene, which was found in the root bark, and a small amount of β-amyrin, a possible precursor of oleanane-type triterpenes, were detected in cell suspension cultures in addition to lupeol, a fundamental form of lupane-type triterpenes. These findings suggest that the absence of glycyrrhizin in undifferentiated cultured cells may be partly due to interruption of the later reactions leading to the synthesis of glycyrrhizin from a triterpenoid intermediate.
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References
Canonica L, Russo G., Bombardelli E (1966) Gazz. Chim. Ital. 96: 833–842
Indrayanto VG, Voelter W, Reinhard E (1983) Chem. Ztg. 107: 238–239
Kamisako W, Morimoto K, Makino I, Isoi K (1984) Plant & Cell Physiol. 25: 1571–1574
Kitagawa I, Zhou JL, T. Taniyama, M. Yoshikawa (1987) Abstr. Ann. Meeting Pharmaceut. Soc. Japan: 337
Kobayashi M, Noguchi K, Sankawa U (1985) Chem. Pharm. Bull. 33: 3811–3816
Linsmaier EM, Skoog F (1965) Physiol. Plant. 18: 100–127
Sagara K, Ito Y, Oshima T, Kawaura M, Misaki T (1985) Chem. Pharm. Bull. 33: 5364–5368
Saitoh T, Shibata S (1969) Chem. Pharm. Bull. 17: 729–734
Tamaki E, Morishita I, Nishida K, Kato K, Matsumoto T (1972), Patent: CA 77 (13) 85879 F, Germany Offen. DE 2146580
Hattori M, Miyachi K, Shu YZ, Kakiuchi N, Namba T (1986) Shoyakugaku Zasshi 40: 406–412
Henry M, Edy AM, Marty B (1984) C. R. Acad. Sci., Ser. 3 299: 899–903
Yoo SC, Kim SS (1976) Kor. J. Pharmacog. 7: 55–57
Vaněk T, Macek T, Beneš I, Novotný L (1985) Phytochemistry 24: 3064–3065
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Hayashi, H., Fukui, H. & Tabata, M. Examination of triterpenoids produced by callus and cell suspension cultures of Glycyrrhiza glabra . Plant Cell Reports 7, 508–511 (1988). https://doi.org/10.1007/BF00272743
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DOI: https://doi.org/10.1007/BF00272743