Summary
A case of testicular feminization is described, who has the karyotype 47,XXY in all analysed metaphases from blood and skin cultures. The question is discussed whether the karyotype 47,XXY is compatible with the syndrome of testicular feminization and which conditions are required to allow the hitherto known transmission of testicular feminization in presence of the gonosomes XXY. A review of literature is given.
Zusammenfassung
Ein Fall von testiculärer Feminisierung wird vorgestellt, der den Karyotyp 47,XXY in allen untersuchten Metaphasen aus Blut- und Hautkulturen hat. Ein solcher Karyotyp legt die Frage nahe, inwieweit sich die Gonosomenkontitution XXY mit dem Syndrom der testiculären Feminisierung und weiterhin mit dem bisher bekannten Vererbungsmodus bei der testiculären Feminisierung vereinbaren läßt. Eine Literaturübersicht wird gegeben.
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Literatur
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St. Josefs-Krankenhaus, Moers.
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Bartsch-Sandhoff, M., Stephan, L., Röhrborn, G. et al. Ein Fall von testiculärer Feminisierung mit dem Karyotyp 47,XXY. Hum. Genet. 31, 59–65 (1976). https://doi.org/10.1007/BF00270400
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DOI: https://doi.org/10.1007/BF00270400