Summary
Dorsomedial frontal cortex (DMFC) was studied in monkeys trained to make visually guided eye or arm movements. Portions of DMFC are involved in the execution of learned, goal-directed behaviors. Many neurons discharge with both eye and hand movements as well as when motor responses are withheld, provided these behaviors are related to the successful execution of the learned task. Similar movements, when carried out at times unrelated to the task, are not accompanied by neuronal activity. Electrical microstimulation produces either arrest of task-related, but not task-unrelated motor acts, or triggers task-related movements. The nature of stimulation elicited responses depends on the task the animal has been trained on and is altered by new training.
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Mann, S.E., Thau, R. & Schiller, P.H. Conditional task-related responses in monkey dorsomedial frontal cortex. Exp Brain Res 69, 460–468 (1988). https://doi.org/10.1007/BF00247300
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DOI: https://doi.org/10.1007/BF00247300