Summary
We have investigated the responses of neurones in the guinea-pig superior colliculus to combinations of visual and auditory stimuli. When these stimuli were presented separately, some of these neurones responded only to one modality, others to both and a few neurones reliably to neither. To bimodal stimulation, many of these neurones exhibited some form of cross-modality interaction, the degree and nature of which depended on the relative timing and location of the two stimuli. Facilitatory and inhibitory interactions were observed and, occasionally, both effects were found in the same neurone at different inter-stimulus intervals. Neurones whose responses to visual stimuli were enhanced by an auditory stimulus were found in the superficial layers. Although visual-enhanced and visual-depressed auditory neurones were found throughout the deep layers, the majority of them were recorded in the stratum griseum profundum. Neurones that responded to both visual and auditory stimuli presented separately and gave enhanced or depressed responses to bimodal stimulation were found throughout the deep layers, but were concentrated in the stratum griseum intermediale and extended into the stratum opticum.
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References
Bisti S, Maffei L, Piccolino M (1974) Visuovestibular interactions in the cat superior colliculus. J Neurophysiol 37: 146–155
Bitar M, Saadé NE, Banna NR, Jabbur SJ (1981) Interactions of inputs from dorsal columns and ventral tracts with visual inputs on single neurons of cat superior colliculus. Brain Res 220: 356–361
Chalupa LM, Rhoades RW (1977) Responses of visual, somatosensory, and auditory neurones in the golden hamster's superior colliculus. J Physiol (Lond) 270: 595–626
Donaldson IML, Long AC (1980) Interactions between extraocular proprioceptive and visual signals in the superior colliculus of the cat. J Physiol (Lond) 298: 85–110
Dräger UC, Hubel DH (1975) Responses to visual stimulation and relationship between visual, auditory, and somatosensory inputs in mouse superior colliculus. J Neurophysiol 38: 690–713
Finlay BL, Schneps SE, Wilson KG, Schneider GE (1978) Topography of visual and somatosensory projections to the superior colliculus of the golden hamster. Brain Res 142: 223–235
Goldberg ME, Robinson DL (1978) Visual system: superior colliculus. In: Masterton RB (ed) Handbook of behavioural neurobiology, Vol 1. Plenum Press, New York, pp 119–164
Gordon B (1973) Receptive fields in deep layers of cat superior colliculus. J Neurophysiol 36: 157–178
Gordon B (1975) Superior colliculus: structure, physiology and possible functions. In: Hunt CC (ed) Physiology series 1,3. Butterworth Press, London, pp 185–231
Gouras P (1967) The effects of light-adaptation on rod and cone receptive field organization of monkey ganglion cells. J Physiol (Lond) 192: 747–760
Harris LR, Blakemore C, Donaghy M (1980) Integration of visual and auditory space in the mammalian superior colliculus. Nature 288: 56–59
Horn G, Hill RM (1966) Responsiveness to sensory stimulation of units in the superior colliculus and subjacent tectotegmental regions of the rabbit. Exp Neurol 14: 199–233
Jassik-Gerschenfeld D (1965) Somesthetic and visual responses of superior colliculus neurones. Nature 208: 898–900
Jay MF, Sparks DL (1984) Auditory receptive fields in primate superior colliculus shift with changes in eye position. Nature 309: 345–347
King AJ, Palmer AR (1983) Cells responsive to free-field auditory stimuli in guinea-pig superior colliculus: distribution and response properties. J Physiol (Lond) 342: 361–381
King AJ, Palmer AR (1984) Interactions between visual and auditory inputs in the guinea-pig superior colliculus. J Physiol (Lond) 350: 64P
Knudsen EI (1982) Auditory and visual maps of space in the optic tectum of the owl. J Neurosci 2: 1177–1194
Levick WR, Zachs JL (1970) Responses of cat retinal ganglion cells to brief flashes of light. J Physiol (Lond) 206: 677–700
McHaffie JG, Stein BE (1982) Eye movements evoked by electrical stimulation in the superior colliculus of rats and hamsters. Brain Res 247: 243–253
Meredith MA, Stein BE (1982) Superior colliculus: interactions of converging multisensory inputs. Neurosci Abstr 8: 205
Meredith MA, Stein BE (1983) Interactions among converging sensory inputs in the superior colliculus. Science 221: 389–391
Meredith MA, Stein BE (1984) Multimodal enhancement and depression in superior colliculus cells is determined by stimulus location. Neuroscience Abstr 10: 298
Nemitz JW, Meredith MA, Stein BE (1984) Temporal determinants of multimodal interactions in superior colliculus cells. Neuroscience Abstr 10: 298
Newman EA, Hartline PH (1981) Integration of visual and infrared information in bimodal neurons of the rattlesnake optic tectum. Science 213: 789–791
Palmer AR, King AJ (1982) The representation of auditory space in the mammalian superior colliculus. Nature 299: 248–249
Paula-Barbosa MM, Sousa-Pinto A (1973) Auditory cortical projections to the superior colliculus in the cat. Brain Res 50: 47–61
Rauschecker JP, Harris LR (1983) Auditory compensation of the effects of visual deprivation in the cat's superior colliculus. Exp Brain Res 50: 69–83
Rhoades RW (1980) Effects of neonatal enucleation on the functional organization of the superior colliculus in the golden hamster. J Physiol (Lond) 301: 383–399
Rhoades RW, DellaCroce DD, Meadows I (1981) Reorganization of somatosensory input to superior colliculus in neonatally enucleated hamsters: anatomical and electrophysiological experiments. J Neurophysiol 46: 855–877
Rupert A, Moushegian G, Galambos R (1963) Unit responses to sound from the auditory nerve of the cat. J Neurophysiol 26: 449–465
Sprague JM, Berlucchi G, Rizzolatti G (1973) The role of the superior colliculus and pretectum in vision and visually guided behaviour. In: Jung R (ed) Handbook of sensory physiology, Vol VII/3,B. Springer, Berlin, pp 27–101
Stein BE, Arigbede MO (1972) Unimodal and multimodal response properties of neurons in the cat's superior colliculus. Exp Neurol 36: 179–196
Stein BE, Magalhães-Castro B, Kruger L (1976) Relationship between visual and tactile representations in cat superior colliculus. J Neurophysiol 39: 401–419
Swadlow HA, Weyand TG, Vera PL (1982) The effect of sudden tactile and auditory stimuli on the visual responses of neurons in the dorsal lateral geniculate nucleus of fully awake rabbits. Neuroscience Abstr 8: 207
Tiao Y-C, Blakemore C (1976) Functional organization in the superior colliculus of the golden hamster. J Comp Neurol 168: 483–504
Updyke BV (1974) Characteristics of unit responses in superior colliculus of the Cebus monkey. J Neurophysiol 37: 896–909
Walls GL (1967) The vertebrate eye and its adaptive radiation. Hafner, New York
Wickelgren BG (1971) Superior colliculus: some receptive field properties of bimodally responsive cells. Science 173: 69–72
Wiener SI, Hartline PH (1984) Multimodal neurons of mouse superior colliculus: magnitude and sign of interaction depend on intermodality delay. Neuroscience Abstr 10: 736
Wurtz RH, Albano JE (1980) Visual-motor function of the primate superior colliculus. Ann Rev Neurosci 3: 189–226
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King, A.J., Palmer, A.R. Integration of visual and auditory information in bimodal neurones in the guinea-pig superior colliculus. Exp Brain Res 60, 492–500 (1985). https://doi.org/10.1007/BF00236934
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DOI: https://doi.org/10.1007/BF00236934