Abstract
A descending volley in response to non-invasive transcranial magnetic stimulation has been recorded from the pyramidal tract in a conscious monkey and identified by means of a collision test. The short latency of the earliest wave was inconsistent with a trans-synaptically mediated activation of pyramidal tract neurones. Considerable variability in the size of this wave was seen in response to a constant stimulus, and isoflurane anaesthetic was shown to depress it markedly. These results are consistent with direct activation of pyramidal tract neurones at a site close to the cell body.
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Baker, S.N., Olivier, E. & Lemon, R.N. Recording an identified pyramidal volley evoked by transcranial magnetic stimulation in a conscious macaque monkey. Exp Brain Res 99, 529–532 (1994). https://doi.org/10.1007/BF00228989
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DOI: https://doi.org/10.1007/BF00228989