Abstract
Methods have been developed to compare full field rod and cone electroretinograms with results of rod and cone static perimetric measurements across the visual field. In a limited number of patients with retinal degeneration, including two subtypes of retinitis pigmentosa, there were close relationships between electroretinographic and psychophysical parameters. Maximum b-wave amplitude and visual field area were highly correlated, as were electroretinographic and perimetric measures of sensitivity loss. Future application of the methods to large numbers of patients with typical retinitis pigmentosa may help elucidate different mechanisms of retinal degeneration.
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References
Massof RW, Wu L, Finkelstein D, Perry C, Starr SJ, Johnson MA. Properties of electroretinographic intensity-response functions in retinitis pigmentosa. Doc Ophthalmol 1984; 57: 279–96.
Arden GB, Carter RM, Hogg CR, Powell DJ, Ernst WJK, Clover GM, Lyness AL, Quinlan MP. A modified ERG technique and the results obtained in X-linked retinitis pigmentosa. Br J Ophthalmol 1983; 67: 419–30.
Massof RW, Finkelstein D. Rod sensitivity relative to cone sensitivity in retinitis pigmentosa. Invest Ophthalmol Vis Sci 1979; 18: 263–72.
Ernst W, Faulkner DJ, Hogg CR, Powell DJ, Arden GB, Vaegan. An automated static perimeter/adaptometer using light emitting diodes. Br J Ophthalmol 1983; 67: 431–42.
Jacobson SG, Voigt WJ, Parel JM, Apáthy PP, Nghiem-Phu L, Myers SW, Patella VM. Automated light and dark-adapted perimetry for evaluating retinitis pigmentosa. Ophthalmology 93: 1986; 1604–11.
Fulton AB, Rushton WA. The human rod ERG: correlation with psychophysical responses in light and dark adaptation. Vision Res 1978; 18: 793–800.
Arden GB, Carter RM, Hogg CR, Powell DJ, Ernst WJK, Clover GM, Lyness AL, Quinlan MP. Rod and cone activity in patients with dominantly inherited retinitis pigmentosa: comparisons between psychophysical and electroretinographic measurements. Br J Ophthalmol 1983; 67: 405–18.
Birch DG, Herman WK, deFaller JM, Disbrow DT, Birch EE. The relationship between rod perimetric thresholds and full field rod ERGs in retinitis pigmentosa. Invest Ophthalmol Vis Sci 1987; 28: 954–65.
Jacobson SG, Borruat FX, Apathy PP. Rod or cone dysfunction: uniocular presentations. Doc Ophthalmol 1986; 63: 63–71.
Apathy PP, Jacobson SG, Nghiem-Phu L, Knighton RW, Parel JM. Computer-aided analysis in automated dark-adapted static perimetry. In: Greve EL, Heijl A, eds. Seventh international visual field symposium. Dordrecht: Martinus Nijhoff/Dr W Junk, 1987; 277–84.
Naka KI, Rushton WAH. S-potentials from colour units in the retina offish (Cyprinidae). J Physiol 1966; 185: 536–55.
Osterberg G. Topography of the layer of the rods and cones in the human retina. Acta Ophthalmol (Kbh) 1935; Suppl VI: 1–102.
Drasdo N, Fowler GW. Non-linear projection of the retinal image in a wide-angle schematic eye. Br J Ophthalmol 1974; 58: 709–14.
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Yagasaki, K., Jacobson, S.G., Apáthy, P.P. et al. Rod and cone psychophysics and electroretinography: Methods for comparison in retinal degenerations. Doc Ophthalmol 69, 119–130 (1988). https://doi.org/10.1007/BF00153692
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DOI: https://doi.org/10.1007/BF00153692