Abstract
The choice of a crop species for use as a manufacturing vehicle for heterologous protein production is a serious one because it will affect every aspect of product development from the construction of transformation vectors to the downstream processing steps necessary for purification. The use of some crops (e.g. soybeans and canota is further limited by patent restrictions on commercial transformation. Transformation of any crop species will generate an enormous amount of variation in recombinant protein expression and agronomic characteristics that must be managed by careful selection and breeding. For some crops this may be a fairly simple matter, whereas for others it may require years to obtain a finished product line. The breeding of transgenic crops has its own unique challenges and should be approached differently than standard plant breeding because the objectives may be very different depending on the product and target market.
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Delaney, D.E. (2002). Choice of Crop Species and Development of Transgenic Product Lines. In: Hood, E.E., Howard, J.A. (eds) Plants as Factories for Protein Production. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2693-1_7
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DOI: https://doi.org/10.1007/978-94-017-2693-1_7
Publisher Name: Springer, Dordrecht
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