Abstract
Adenosine has several actions on the respiratory system. Given into the common carotid artery (i.c.), it increases carotid body chemoreceptor activity in the cat (McQueen and Ribeiro, 1981: 1983), administered into the cerebral ventricles of the rat it causes respiratory depression (Hedner et al., 1982). Other actions of adenosine on respiration include its bronchoconstrictor effect in asthmatic subjects, an effect antagonised by methylxanthines and aggravated by the release of adenosine into the circulation following antigen provocation (Church et al., 1985): adenosine also causes relaxation of guinea pig trachea in vitro via an A2 adenosine receptor (Brown and Collis, 1982).
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References
Berne, R.M. (1980). Circ.Res., 47, 807
Biscoe, T.J. (1971). Physiol. Rev., 51, 437.
Brown, C.M. and Collis, M.G. (1982). Br. J. Pharmac., 76, 381.
Church, M.K., Benyon, R.C., Hughes, P.J., Cushley, M.J., Mann, J.S. and Holgate, S.T. (1985). In, Purines: Pharmacology and Physiological Roles, T.W. Stone (ed.), MacMillan, London, pp.175.
Hedner, T., Hedner, J., Wessberg, P. and Jonason, J. (1982). Neurosci. Letts., 33, 147.
Horn, N.M., Hasan, F.F. and Waters, R. (1984). In, The Pheripheral Arterial Chemoreceptors, D.J. Pallot (ed.) Croom Helm, London, pp 345.
Kusachi, S., Thompson, R.D. and Olsson, R.A. (1984). J. Pharmac. exp. Ther., 227, 316
Mcqueen, D.S. and Ribeiro, J.A. (1981). Br. J. Pharmac., 74, 129.
Mcqueen, D.S. and Ribeiro, J.A. (1983). Br. J. Pharmac., 80, 347.
Ribeiro, J.A. and McQueen, D.S. (1986). In, Chemoreceptors in Respiratory Control, J.A. Ribeiro and D.J. Pallot (eds.).
Ribeiro, J.A. and Sebastiao, A.M. (1986). Prog. Neurobiol., (in the press).
Stone, T.W. (1985). Trend Pharmac. Sci., 5, 492
Ukena, D., Bohme, E. and Schwabe, U. (1984). Naunyn-Schmiedeberg’s Arch. Pharmac, 327, 36
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© 1987 J.A. Ribeiro and David J. Pallot
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Monteiro, E.C., Ribeiro, J.A. (1987). Adenosine Modulation of Respiration Mediated by Carotid Body Chemoreceptors. In: Ribeiro, J.A., Pallot, D.J. (eds) Chemoreceptors in Respiratory Control. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-1155-1_36
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DOI: https://doi.org/10.1007/978-94-015-1155-1_36
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