Abstract
The time has come to dissolve the concept of dominance in genetics. The concept is a vestige of history, a frozen accident that may have aided Mendel’s important discovery but is hardly essential as a basic principle of genetics (section 2). Moreover, the concept of dominance is ill-framed and often misleading in terms of heredity, natural selection, and molecular and cellular processes (section 3). More direct language is available to refer to the key relevant principles in inheritance and the phenotypic expression of genetic states (section 4).
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Bateson, W. “The Facts of Heredity in the Light of Mendel’s Discovery.” In Reports to the Evolution Committee of the Royal Society, London (I), W. Bateson, E.R. Saunders, eds. London: Harrison and Sons, 1902.
Brannigan, A. “The Law Valid for Pisum and the Reification of Mendel.” In The Social Basis of Scientific Discoveries. Cambridge: Cambridge University Press, 1981.
Burian R.M. How the choice of experimental organism matters: epistemological reflections on an aspect of biological practice. Journal of the History of Biology 1993; 26:351–67
Clarke, A.E., Fujimura, J., eds., The Right Tools for the Job: At Work in Twentieth-Century Life Sciences. Princeton: Princeton University Press, 1992.
Curtis, W.C., Guthrie, M.J., Textbook of General Zoology, 2nd ed. New York: John Wiley & Sons, 1933.
Darden, L., Theory Change in Science: Strategies from Mendelian Genetics. Oxford: Oxford University Press, 1991.
Donovan M.P. The vocabulary of biology and the problem of semantics. Journal of College Science Teaching 1997; 26:381–2
Falk R. The rise and fall of dominance. Biology and Philosophy 2001; 16:285–323
Guilfoile P. Wrinkled peas and white-eyed fruit flies: the molecular basis of two classical genetic traits. American Biology Teacher 1997; 59:92–5
Hartl D.L., Orel V. What did Gregor Mendel think he discovered? Genetics 1992; 131:245–53
Kroeber, E., Wolff, W.H., Weaver, R.L., Biology, 2nd ed. Lexington, MA: D.C. Heath and Co., 1969.
Lakoff, G., Johnson, M., Metaphors We Live By. Chicago: University of Chicago Press, 1980.
Lewin, B., Genes VI. Oxford: Oxford University Press, 1997.
Lock, R.H., Recent Progress in the Study of Variation, Heredity, and Evolution. New York: Dutton, 1906.
Mendel, G. “Versuche fiber Pflanzenhybriden [Experiments Concerning Plant Hybrids],” 1866. Reprinted in Fundamanta Genetica, J. Kieneck, ed. Prague: Anthropological Publications, Oosterhout; Moravian Museum, Bmo; and Czech Academy of Sciences, 1966a. Translation reprinted in The Origin of Genetics: A Mendel Source Book, C. Stern, E. Sherwood, eds. San Francisco: W.H. Freeman, 1966. Translation by C.T. Druery and W. Bateson. Available at: MendelWeb, http://www.netspace.org.
Mendel, G. “On Hieracium-Hybrids Obtained by Artificial Fertilization,” 1869. Translation reprinted in The Origin of Genetics: A Mendel Source Book, C. Stern, E. Sherwood, eds. San Francisco: W.H. Freeman, 1966.
Moon, T.J., Biology for Beginners. New York: Henry Holt, 1921.
Morgan, T.H., Sturtevant, A.H., Muller, H.J., Bridges, C.B., The Mechanism of Mendelian Heredity. New York: Henry Holt, 1915.
Olby R C William Bateson’s introduction of Mendelism to England: a reassessment. British Journal for the History of Science 1987; 20:399–420
Olby R.C. Mendel, Mendelism and genetics, 1997. Available at: MendelWeb, http://www.netspace.org/MendelWeb/.
OMIMTM. Center for Medical Genetics, Johns Hopkins University, Baltimore, MD, and National Center for Biotechnology Information. Bethesda, MD: National Library of Medicine, 1997. Available at: http://www.ncbi.nlm.nih.gov/omim/.
Orel, V. “Heredity before Mendel.” In Gregor Mendel: The First Geneticist. Translation by S. Finn. Oxford: Oxford University Press, 1996.
Rodgers J. Mechanisms Mendel never knew. Mosaic 1991; 22:2–11
Russell, P.J., Genetics,3rd ed. New York: Harper Collins, 1992.
Sapp, J. “The Nine Lives of Gregor Mendel.” In Experimental Inquiries, H.E. Le Grand, ed. Dordrecht: Kluwer Academic Press, 1990.
Wilkie A.O.M. The molecular basis of genetic dominance. Journal of Medical Genetics 1994; 31:89–98
Wimsatt, W. “False Models as a Means to Truer Theories.” In Neutral Models in Biology, M. Nitecki, A. Hoffman, eds. Oxford: Oxford University Press, 1987.
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Allchin, D. (2002). Dissolving Dominance. In: Parker, L.S., Ankeny, R.A. (eds) Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society. Philosophy and Medicine, vol 75. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0269-1_3
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DOI: https://doi.org/10.1007/978-94-010-0269-1_3
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