Summary
The aim of the presentation is to give a comprehensive picture about the different methods used for the synthesis of chemically modified cyclodextrin derivatives with well defined and characterized structures. The efficiency of the different chromatographic and spectroscopic methods used for the structure elucidation of CD-derivatives are treated and estimated.
New and modified alkylation procedures for the preparation of fully and partially protected β-cyclodextrin derivatives are treated and reviewed. The utilisation of the compounds are discussed in detail.
Reduction of 6-bromo-6-deoxy-β-cyclodextrin derivatives, nucleophilic displacement of the bromo-compounds by sodium azide, reduction of the azides and also the introduction of new reagents in the field of CD-chemistry are demonstrated.
13C-NMR spectra of the synthesized compounds demonstrate the structure postulated.
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Lipták, A., Fügedi, P., Szurmai, Z., Imre, J., Nánási, P., Szejtli, J. (1982). The Chemistry of Cyclodextrin Derivatives. In: Szejtli, J. (eds) Proceedings of the First International Symposium on Cyclodextrins. Advances in Inclusion Science, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7855-3_34
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DOI: https://doi.org/10.1007/978-94-009-7855-3_34
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