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Active Site Metals as Probes of Local Conformation and Function of Enzymes

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Structural and Functional Aspects of Enzyme Catalysis

Abstract

Metals play roles in catalysis, hormonal, and other regulatory functions and their control, the synthesis and stabilization of the structure of macromolecules, muscle contraction, nerve conduction, and transport. Cobalt, copper, iron, magnesium, manganese, molybdenum, nickel, zinc, and yet others are known to be essential, many of them in the mechanism of action of particular enzymes.

Dedicated to Professor Dr. Helmut Holzer on the occasion of his 65th Birthday, in appreciation of his contributions to Biological Chemistry

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Author information

Authors and Affiliations

  1. Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, 250 Longwood Avenue, Boston, MA, 02115, USA

    B. Vallee

Authors
  1. B. Vallee
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Editor information

Editors and Affiliations

  1. Physiologisch-Chemisches Institut, Technische Universität, Biedersteiner Straße 29, D-8000, München 40, Germany

    Hermann Eggerer

  2. Max-Planck-Institut für Biochemie, Am Klopferspitz, D-8033, Martinsried, Germany

    Robert Huber

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© 1981 Springer-Verlag Berlin Heidelberg

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Vallee, B. (1981). Active Site Metals as Probes of Local Conformation and Function of Enzymes. In: Eggerer, H., Huber, R. (eds) Structural and Functional Aspects of Enzyme Catalysis. Colloquium der Gesellschaft für Biologische Chemie 23.–25. April 1981 in Mosbach/Baden, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81738-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-81738-0_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81740-3

  • Online ISBN: 978-3-642-81738-0

  • eBook Packages: Springer Book Archive

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