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Assessment of Erythema: A Comparison Between the Naked Eye and Laser Doppler Flowmetry

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Current Topics in Contact Dermatitis

Summary

Erythema is an essential part of the contact reaction and can be quantified by laser Doppler flowmetry, which records skin blood flow. Healthy subjects were exposed to solvents and nicotinates for different periods of time and the skin test sites were then assessed by laser Doppler flowmetry as well as by the naked eye. It is concluded that the naked eye cannot detect erythema until the skin blood flow has increased three to four times.

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References

  1. Goldsmith LB, Friberg SE, Wahlberg JE (1988) The effect of solvent extraction on the lipids of the stratum corneum in relation to observed, immediate whitening of the skin. Contact Dermatitis 19: 348–350.

    Article  PubMed  CAS  Google Scholar 

  2. Klauder JV, Brill FA (1947) Correlation of boiling ranges of some petroleum solvents with irritant action on skin. Arch Dermatol 56: 197–215.

    Article  CAS  Google Scholar 

  3. Nilsson GE, Otto U, Wahlberg JE (1982) Assessment of skin irritancy in man by laser Doppler flowmetry. Contact Dermatitis 8: 401–406.

    Article  PubMed  CAS  Google Scholar 

  4. Salerud EG, Nilsson GE (1986) Integrating probe for tissue laser Doppler flowmeters. Med Biol Eng Comput 24: 415–419.

    Article  PubMed  CAS  Google Scholar 

  5. Wahlberg JE (1984) Erythema-inducing effects of solvents following epicutaneous administration to man — studied by laser Doppler flowmetry. Scand J Work Environ Health10: 159–162.

    Article  PubMed  CAS  Google Scholar 

  6. Wahlberg JE, Nilsson GE (1984) Skin irritancy from propylene glycol. Acta Derm Venereol (Stockh) 64: 286–290.

    CAS  Google Scholar 

  7. Wahlberg JE, Wahlberg ENG (1987) Quantification of skin blood flow at patch test sites. Contact Dermatitis 17: 229–233.

    Article  PubMed  CAS  Google Scholar 

  8. Weil CS, Scala RA (1971) Study of intra-and interlaboratory variability in the results of rabbit eye and skin irritation tests. Toxicol Appl Pharmacol 19: 276–360.

    Article  PubMed  CAS  Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Wahlberg, J.E. (1989). Assessment of Erythema: A Comparison Between the Naked Eye and Laser Doppler Flowmetry. In: Frosch, P., Dooms-Goossens, A., Lachapelle, JM., Rycroft, R.J.G., Scheper, R.J. (eds) Current Topics in Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74299-6_108

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  • DOI: https://doi.org/10.1007/978-3-642-74299-6_108

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74301-6

  • Online ISBN: 978-3-642-74299-6

  • eBook Packages: Springer Book Archive

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