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Tardive Dyskinesia: Prevalence, Incidence, and Risk Factors

  • Conference paper
Dyskinesia

Part of the book series: Psychopharmacology Supplementum ((PSYCHOPHARM,volume 2))

Abstract

Tardive dyskinesia remains a major concern in psychiatry. Epidemiologic data suggest that the prevalence of the disorder has increased over the past two decades. The average prevalence of TD across various populations is 15%–20%. Abnormal involuntary movements appear to be at least three times more prevalent in neuroleptic-treated patients than in patients not exposed to such drugs.

The incidence of TD in a young adult (mean age 27) population is 14% after 4 years of cumulative neuroleptic exposure. The majority of these cases are mild and the condition does not appear to progress in most individuals despite continued neuroleptic exposure.

Age remains the single most important risk factor for the development of TD. Recent investigations suggest that patients with affective illness may also be more vulnerable.

This work was supported by NIMH contract NO 278-81-0032 and NIMH grant 32369

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Author information

Authors and Affiliations

  1. Department of Psychiatry, Long Island Jewish-Hillside Medical Center, Glen Oaks, NY, 11004, USA

    J. Lieberman

Authors
  1. J. M. Kane
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  2. M. Woerner
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  3. J. Lieberman
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Editor information

Editors and Affiliations

  1. Medical Research, Psychiatry and Neurology Services at the Veterans Administration Medical Center, USA

    Daniel E. Casey MD (Clinical Investigator, Associate Professor, Collaborative Scientist) (Clinical Investigator, Associate Professor, Collaborative Scientist)

  2. Departments of Psychiatry and Neurology at the Oregon Health Sciences University, 97207, Portland, OR, USA

    Daniel E. Casey MD (Clinical Investigator, Associate Professor, Collaborative Scientist) (Clinical Investigator, Associate Professor, Collaborative Scientist)

  3. Oregon Regional Primate Research Center, 97006, Beaverton, OR, USA

    Daniel E. Casey MD (Clinical Investigator, Associate Professor, Collaborative Scientist) (Clinical Investigator, Associate Professor, Collaborative Scientist)

  4. Intramural Research Program, National Institute of Neurological and Communicative Disorders and Stroke, Department of Health and Human Services, National Institute of Health, 20205, Bethesda, MD, USA

    Thomas N. Chase MD (Director) (Director)

  5. H. Lundbeck A/S, Ottiliavej 7-9, DK-2500, Copenhagen-Valby, Denmark

    Anne Vibeke Christensen MSc Pharm, DSc (Vice-President, Director of Research) (Vice-President, Director of Research)

  6. Department AEH, Sct. Hans Mental Hospital, DK-4000, Roskilde, Denmark

    Jes Gerlach MD

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© 1985 Springer-Verlag Berlin Heidelberg

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Kane, J.M., Woerner, M., Lieberman, J. (1985). Tardive Dyskinesia: Prevalence, Incidence, and Risk Factors. In: Casey, D.E., Chase, T.N., Christensen, A.V., Gerlach, J. (eds) Dyskinesia. Psychopharmacology Supplementum, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70140-5_9

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  • DOI: https://doi.org/10.1007/978-3-642-70140-5_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70142-9

  • Online ISBN: 978-3-642-70140-5

  • eBook Packages: Springer Book Archive

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