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Mutagenic Activity of Cigarette Smoke

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Mutations in Man

Abstract

Smoking is made responsible for a variety of cancers in man and it is estimated that some 30% of all cancer deaths in the USA are caused by smoking (Doll and Peto 1981; The Health Consequences of Smoking 1982; Smoking and Health 1979). The finding that cigarette smoke is mutagenic in a variety of test systems including somatic cells of man may be helpful to a better understanding of the mechanisms by which smoking leads to cancer. These data also support the mutation theory of the origin of cancer which was already formulated by Boveri in 1914 and elaborated by Bauer in 1928 (see also Bauer 1963).

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Authors and Affiliations

  1. Institut für Genetik, Freie Universität Berlin, Arnimallee 5-7, 1000, Berlin 33, Germany

    G. Obe

  2. Institut für Statistik und mathematische Wirtschaftstheorie, Universität Karlsruhe, 6380, 7500, Karlsruhe 1, Germany

    W. D. Heller

  3. Dermatologische Klinik und Poliklinik der Technischen Universität München, Biedersteiner Straße 29, 8000, München 40, Germany

    H.-J. Vogt

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  1. G. Obe
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  2. W. D. Heller
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  3. H.-J. Vogt
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Editors and Affiliations

  1. Institut für Genetik, Freie Universität Berlin, Arnimallee 5-7, 1000, Berlin 33, Germany

    Günter Obe

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© 1984 Springer-Verlag Berlin Heidelberg

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Obe, G., Heller, W.D., Vogt, HJ. (1984). Mutagenic Activity of Cigarette Smoke. In: Obe, G. (eds) Mutations in Man. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69530-8_11

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  • DOI: https://doi.org/10.1007/978-3-642-69530-8_11

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