Skip to main content

Experiences in the Formalisation and Verification of Medical Protocols

  • Conference paper
Artificial Intelligence in Medicine (AIME 2003)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 2780))

Included in the following conference series:

Abstract

Medical practice protocols or guidelines are statements to assist practitioners and patient decisions about appropriate health care for specific circumstances. In order to reach their potential benefits, protocols must fulfill strong quality requirements. Medical bodies worldwide have made efforts in this direction, mostly using informal methods such as peer review of protocols. We are concerned with a different approach, namely the quality improvement of medical protocols by formal methods. In this paper we report on our experiences in the formalisation and verification of a real-world medical protocol. We have fully formalised a medical protocol in a two-stage formalisation process. Then, we have used a theorem prover to confirm whether the protocol formalisation complies with certain protocol properties. As a result, we have shown that formal verification can be used to analyse, and eventually improve, medical protocols.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Field, M., Lohr, K. (eds.): Clinical Practice Guidelines: Directions for a New Program. National Academy Press, Washington (1992)

    Google Scholar 

  2. Woolf, S., Grol, R., Hutchinson, A., Eccles, M., Grimshaw, J.: Potential benefits, limitations, and harms of clinical guidelines. British Medical Journal 318, 527–530 (1999)

    Google Scholar 

  3. Clayton, P., Hripsak, G.: Decision support in healthcare. Int. J. of Biomedical Computing 39, 59–66 (1995)

    Article  Google Scholar 

  4. AGREE Collaboration: Appraisal of Guidelines for Research & Evaluation (AGREE) Instrument (2001), Obtained in http://www.agreecollaboration.org/

  5. Balser, M., Reif, W., Schellhorn, G., Stenzel, K., Thums, A.: Formal system development with KIV. In: Maibaum, T. (ed.) FASE 2000. LNCS, vol. 1783, p. 363. Springer, Heidelberg (2000)

    Chapter  Google Scholar 

  6. Shahar, Y., Miksch, S., Johnson, P.: The Asgaard project: a task-specific framework for the application and critiquing of time-oriented clinical guidelines. AI in Medicine 14, 29–51 (1998)

    Google Scholar 

  7. AAP: American Academy of Pediatrics. Practice parameter: management of hyperbilirubinemia in the healthy term newborn. Pediatrics 94, 558–565 (1994)

    Google Scholar 

  8. Elkin, P., Peleg, M., Lacson, R., Bernstam, E., Tu, S., Boxwala, A., Greenes, R., Shortliffe, E.: Toward Standardization of Electronic Guidelines. MD Computing 17, 39–44 (2000)

    Google Scholar 

  9. Miksch, S.: Plan Management in the Medical Domain. AI Communications 12, 209–235 (1999)

    Google Scholar 

  10. Fox, J., Johns, N., Lyons, C., Rahmanzadeh, A., Thomson, R., Wilson, P.: PROforma: a general technology for clinical decision support systems. Computer Methods and Programs in Biomedicine 54, 59–67 (1997)

    Article  Google Scholar 

  11. Moszkowski, B.: A temporal logic for multilevel reasoning about hardware. IEEE Computer 18, 10–19 (1985)

    Google Scholar 

  12. MAJIC: MAJIC Steering Committee Meets. MAJIC Newsletter 1 (1998)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Marcos, M., Balser, M., ten Teije, A., van Harmelen, F., Duelli, C. (2003). Experiences in the Formalisation and Verification of Medical Protocols. In: Dojat, M., Keravnou, E.T., Barahona, P. (eds) Artificial Intelligence in Medicine. AIME 2003. Lecture Notes in Computer Science(), vol 2780. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-39907-0_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-39907-0_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-20129-8

  • Online ISBN: 978-3-540-39907-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics