Abstract
In the field of cancer research, there is not only a flood of original articles, but also an abundance of reviews and books on a variety of topics, including chemotherapy. Several reviews have appeared in the past few years dealing with drugs of the podophyllum type, particularly etoposide [1]. So why publish yet another one?
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Abbreviations
- VM:
-
teniposide
- VP:
-
etoposide
- P:
-
podophyllotoxin
- D:
-
4’-demethyl
- E:
-
epi
- G:
-
glucoside
- B:
-
benzylidene
- n:
-
number of experiments
- i. v.:
-
intravenous(ly)
- i. p.:
-
intraperitoneal(ly)
- s. c.:
-
subcutaneous(ly)
- p. o.:
-
per os (oral)
- n. t.:
-
not tested
References
B.F. Issell, F.M. Muggia and S.K. Carter (eds): Etoposide (VP-16), current status and new developments. Academic Press, Orlando 1984.
M.G. Kelly and J.L. Hartwell: J. natl Cancer Inst. 14, 961 (1954).
I.W. Kaplan: New Orleans Med. Surg. J. 94, 388 (1942).
L.S. King and M. Sullivan: Science 104, 244 (1946).
V. Podwyssotzki: Arch. exp. Path. Pharmac. 13, 29 (1880).
J.L. Hartwell and A.W. Schrecker: J. Am. chem. Soc. 73, 2909 (1951).
W.J. Gensler and C.D. Gatsonis: J. Am. chem. Soc. 84, 1748 (1962); J. org. Chem. 37, 4004 (1966).
J.L. Hartwell and W.E. Detty: J. Am. chem. Soc. 70, 2833 (1948); 72, 246 (1950).
H. Kofod and C. Jorgensen: Acta chem. scand. 8, 1296 (1954); 9, 346 (1955).
R. Chatterjee and S.K. Mukerjee: Indian J. Physiol, all. Sci. 4, 61 (1950).
R. Chatterjee and D.K. Datta: Indian J. Physiol, all. Sci. 4, 1 (1950).
J.L. Hartwell and A.W. Schrecker: Fortschr. Chem. org. NatStoffe 15, 83 (1958).
M.V. Nadkarni, J.L. Hartwell, P.B. Maury and J. Leiter: J. Am. chem. Soc. 75, 1308 (1953).
A. Stoll, J. Renz and A. von Wartburg: J. Am. chem. Soc. 76, 3103 (1954).
A. Stoll, J. Renz and A. von Wartburg: Helv. chim. Acta 37, 1747 (1954).
A. Stoll, A. von Wartburg, E. Angliker and J. Renz: J. Am. chem. Soc. 76, 5004 (1954).
A. Stoll, A. von Wartburg, E. Angliker and J. Renz: J. Am. chem. Soc. 76, 6413 (1954).
A. Stoll, A. von Wartburg and J. Renz: J. Am. chem. Soc. 77, 1710 (1955).
A. von Wartburg, E. Angliker and J. Renz: Helv. chim. Acta. 40, 1331 (1957).
H. Stähelin: Med. exp. 7, 92 (1962).
H. Stähelin: unpublished results.
C. Keller, M. Kuhn, A. von Wartburg and H. Stähelin: unpublished results (1963/64).
M. Kuhn and A. von Wartburg: Helv. chim. Acta 46, 2127 (1963).
H. Stähelin and A. Cerletti: Schweiz. med. Wschr. 94, 1490 (1964).
J.D. Loike, S.B. Horwitz and A.P. Grollmann: The Pharmacologist 76, 209 (1974).
B.H. Long and A. Minocha: Proc. Am. Ass. Cancer Res. 24, 1271 (1983).
W. Ross, T. Rowe, B. Glisson, J. Yalowich and L. Liu: Cancer Res. 44, 5857 (1984).
M. Kuhn and A. von Wartburg: Helv. chim. Acta 57, 1631 (1968).Helv. chim. Acta 52, 948 (1969).
A. Rüegger, M. Kuhn, H. Lichti, H. R. Loosli, R. Huguenin, C. Quiquerez and A. von Wartburg: Helv. chim. Acta 59, 1075 (1976).
J. F. Borel, A. Rüegger and H. Stähelin: Experientia 32, 111 (1976).
H. Stähelin: Internal Report of 31 Jan. 1972.
T. Kaneko and H. Wong: Tetrahedron Lett. 28, 511 (1987) and earlier work quoted here.
D.I. Macdonald and T. Durst: J. org. Chem. 53, 3663 (1988).
A.W. Schrecker and J.L. Hartwell: J. org. Chem. 27, 381 (1956).
T.J. Petcher, H.P. Weber, M. Kuhn and A. von Wartburg: J. chem. Soc., Perkin Trans. 77, 288 (1973).
K.R. Beutner: Semin. Dermat. 6, 10 (1987).
L. Wilson: Ann. N. Y. Acad. Sci. 253, 213 (1975).
P. Dustin: Microtubules. Springer-Verlag, Berlin 1978.
A. Cerletti, H. Emmenegger and H. Stähelin: Actual, pharmac. (Paris) 72, 103 (1959).
H. Emmenegger, H. Stähelin, J. Rutschmann, J. Renz and A. von Wartburg: Arzneimittel-Forsch. (Drug Res.) 77, 327, 459 (1961).
H. Stähelin: Eur. J. Cancer 6, 303 (1970).
J. Leiter, V. Downing, J.L. Hartwell and M.J. Shear: J. natl Cancer Inst. 70, 1273 (1950).
M. Kuhn and A. von Wartburg: Helv. chim. Acta 50, 1546 (1967).
A. von Wartburg, M. Kuhn and H. Lichti: Helv. chim. Acta 47, 1203 (1964).
A. Stoll, J. Rutschmann, A. von Wartburg and J. Renz: Helv. chim. Acta 39, 993 (1956).
H. Stähelin: Planta med. 22, 336 (1972).
A. Weder: Schweiz. med. Wschr. 58, 625 (1958).
A. Goldin, A.A. Serpick and N. Mantel: Cancer Chemother. Rep. 50, 173 (1966).
Sandoz Ltd.: Exposé über die Cytostatica SP-I und SP-G Sandoz (1963).
H. Stähelin, K. Zehnder and F. Kalberer: unpublished observations (1962).
K. Batz, F. Kalberer and H. Stähelin: Experientia 20, 524 (1964).
H. Stähelin: Experientia 76, 306 (1960).
H. Stähelin: unpublished observations (1964).
S. Lazary and H. Stähelin: In: 5th Internat. Congr. Chemother. Vol. III, p. 317. Ed. K.H. Spitzy. Verlag Wiener med. Akademie, Vienna 1967.
D Wiesinger: unpublished observations (1967).
A. Benz: Dermatologica 136, 368 (1968).
W.R. Schalch, W. Meier-Ruge and J. Grauwiler: unpublished results (1962–1965).
W. Meier-Ruge, F. Kalberer and J. Grauwiler: Klin. Wschr. 42, 1024.
E M. Lemmel and K. Nouza: Fol. biol. 12, 253 (1966).
O. Hubacher: Krebsarzt 76, 369 (1961); Schweiz, med. Wschr. 97, 1316 (1961).
A. Ravina: Presse méd. 77, 807 (1963).
G. Falkson, A.G. Sandison and J. van Zyl: S. Afr. J. Radiol. 2, 1 (1964).
O. Stamm: Münch, med. Wschr. 106, 41 (1964).
E. Aquilini: Minerva ginec. 16, 902 (1964).
M. Gosalvez: Rev. esp. One. 11, 357 (1964).
V. Larsen, J. Brockner and O. Storm: Acta chir. scand. Suppl. 343, 203 (1965).
V.K. Vaitkevicius and M.L. Reed: Cancer Chemother. Rep. 50, 565 (1966).
H M. Beumer and W.M. Porton: Ned. T. Geneesk. 110, 1877 (1966).
S. Krishnamurthi, V. Shanta and M.K. Nair: Cancer 20, 822 (1967).
K.H. Gebhardt and R. Becher: Med. Welt 78, 1705 (1967).
C.G. Schmidt: In: Krebsforschung und Krebsbekämpfung, Vol. VI, p. 309. Ed. E. Bock. Urban und Schwarzenberg, München 1967.
R.C. Chakravorty, S.K. Sarkar, S. Sen and B. Mukerji: Br. J. Cancer 27, 33 (1967).
R.A. Estévez, A.A. Carugati, O.T. Estévez and M. Speroni: Rev. Lat. Amer. Quimioter. Antineoplas. 2, 101 (1968).
C.L.P. Trüb and L. Pohlschmidt: Therapie Gegenw. 117, 358 (1978).
M. Neiger: Practica Oto-rhino-laryng. 26, 268 (1964).
K.A. Newton, G. Westbury and W.F. White: Cancer Chemother. Rep. 43, 33 (1964).
K.A. Newton: Br. J. Radiol. 40, 823 (1967).
J. Bilder: Zentbl. Chir. 95, 337 (1968).
H. Limburg and M. Krähe: Dtsch. med. Wschr. 89, 1938 (1964).
O. Stamm and H. Stähelin: Cancer 18, 1096 (1965).
J. Gomez Orbaneja, L. Iglesias Diez and J.L. Sanchez Lozano: Dermatologica 145, 348 (1972).
A. Wiskemann: Strahlentherapie 143, 338 (1972).
K. Chlud, E. Prohaska and Ch. Pfaller: Z. Rheumaforsch. 26, 250 (1967).
K. Chlud, E. Prohaska, J. Zeitlhofer, Ch. Pfaller and B. Friza: Münch. med. Wschr. 110, 88 (1968).
K. Chlud: Münch. med. Wschr. 111, 2503 (1969).
E. Neumayer: Wien. med. Wschr. 119, 281 (1969).
W. Danielczyk: Wien. Klin. Wschr. 82, 691 (1970).
Sandoz Ltd.: Document on immunosuppressive effects of SP-I (1968).
B. Norberg, K. Berglund, U. Edström. L. Rydgren and G. Sturfeldt: Scand. J. Rheumat. 14, 211 (1985).
J. Rutschmann and J. Renz: Helv. chim. Acta 42, 890 (1959).
T.W. Doyle: In: IsScil et al. (Eds) ref. [1], p. 15 (1984).
H. Stähelin: Presented at 10th Int. Congr. Cell Biology, Paris (1960).
M. Kuhn und A. von Wartburg: Experientia 19, 391 (1963).
J. Renz, M. Kuhn und A. von Wartburg: Justus Liebigs Annln Chem. 681, 201 (1965).
R. Chatterjee and S.C. Chakravarti: J. Am. Pharmac. Ass. 41, 415 (1952).
E. Schreier: Helv. chim. Acta 46, 15 (1963).
E. Schreier: Helv. chim. Acta 47, 1529 (1964).
M. Kuhn, C. Keller-Juslen and A. von Wartburg: Helv. chim. Acta 52, 944 (1969).
M. Kuhn and A. von Wartburg: Helv. chim. Acta 51, 163 (1968).
M. Kuhn and A. von Wartburg: Helv. chim. Acta 51, 1631 (1968).
C. Keller-Juslen, M. Kuhn, A. von Wartburg and H. Stähelin: J. med. Chem. 14, 936 (1971).
W. Kreis and A. Soricelli: J. Cancer Res. clin. One. 95, 233 (1979).
W.C. Rose, G.A. Basler, S.W. Mamber, M. Saulnier, A.M. Casazza and S.K. Carter: Proc. Am. Ass. Cancer Res. 29, 353 (1988).
C.K. Mirabelli, J.O. Bartus, S.M. Mong, G.A. Hofmann, H.F. Bartus, M.R. Mattern, R. Gupta and R.K. Johnson: Proc. Am. Ass. Cancer Res. 29, 328 (1988).
H. Stähelin: 9th Int. Cancer Congr., Tokyo, Abstracts, vol. I, p. 342, 1966.
P.I. Clark and M.L. Slevin: Clin. Pharmacokinet. 12, 223 (1987).
F. Zavala, D. Guenard, J.P. Robin and E. Brown: J. med. Chem. 23, 546 (1980).
M. Maturova, J. Malinsky and F. Santavy: J. natl Cancer Inst. 22, 297 (1959).
O. Buchardt, R.B. Jensen, H.F. Hansen, P.E. Nielsen, D. Andersen and I. Chinoin: J. pharm. Sci. 75, 1076 (1986).
H. Stähelin: Proc. Am. Ass. Cancer Res. 10, 86 (1969).
H. Stähelin: Eur. J. Cancer 9, 215 (1973).
A. Stoudemire, N. Baker and T.L. Thompson: Am. J. Psychiat. 138, 1505(1981).
J. Venditti: Cancer Chemother. Rep. 55, 35 (1971).
W. Achterrath, N. Niederle and R. Raettig: In: Etoposid, derzeitiger Stand und neue Entwicklungen in der Chemotherapie maligner Neoplasien, p. 1. Eds S. Seeber, G.A. Nagel, W. Achterrath, C.G. Schmidt and R. Raettig. W. Zuckschwerdt, München 1981.
R. Raettig, N. Niederle and W. Achterrath: In: Etoposid (VP 16–213) in der Therapie maligner Erkrankungen, p. 3. Eds J. Schwarzmeier, E. Deutsch and K. Karrer. Springer-Verlag, Wien/New York 1984.
W.C. Rose and W.T. Bradner: In: B.F. IsScil et al., ref. [1], p. 33 (1984).
P. Dombernowsky and N.I. Nissen: Eur. J. Cancer 12, 181 (1976).
T. Colombo, M. Broggini, M. Vaghi, G. Amato, E. Erba and M. D’Incalci: Eur. J. Cancer clin. One. 22, 173 (1986).
M. Rozencweig, D. VonHoff, J. E. Henney and F. M. Muggia: Cancer 40, 334 (1977).
S. Lazary and H. Stähelin: Experientia 24, 1171 (1968).
J. F. Borel, C. Feurer, H. U. Gubler and H. Stähelin: Agents Actions 6, 468 (1976).
S. Lazary: unpublished results.
Morita, A. Haji, A. Goto, N. Hattori and Y. Hasegawa: Fol. pharmac. jap. 87, 77 (1986).
D. Wiesinger: unpublished results.
W. Gassmann, H. U. Wottge, H. Loeffler and W. Müllerruchholtz : Bone Marrow Transplant. 3 (Suppl. 1), 206 (1988).
Sandoz Pharma: Preclinical Brochure “VM 26, Cytostatic” (1967).
W. Calame, R. van der Waals, N. Douwes-Idema, H. Mattie and R. van Furth: Antimicrob. Agents Chemother. 32, 1456 (1988).
Y. Nishiyama, H. Fujioka, T. Tsurumi, N. Yamamoto, K. Maeno, S. Yoshida and K. Shimokata: J. gen. Virol. 68, 913 (1987).
T. Markkanen, M.L. Mäkinen, E. Maunuksela and P. Himanen: Drugs. exp. clin. Res. 7, 711 (1981).
H. Stähelin: In: Experimentelle und klinische Erfahrungen mit Podphyllinderivaten in der Tumortherapie, p. 19 Eds H. Lettré and S. Witte. Schattauer, Stuttgart 1967.
H. Stähelin: In: G. K. Daikos, Progress in Chemotherapy, Vol. III, p. 819. Proc. 8th Internat. Congr. Chemother., Athens 1973, Hellenic Soc. Chemotherapy, Athens 1974.
H. Stähelin: In: Workshop on clinical usefulness of cell kinetic information for tumour chemotherapy, p. 21 Ed. M. van Putten. REP-TNO, Rijswijk 1974.
H.E. Skipper, F.M. Schabel, M.W. Trader and J.R. Thomson: Cancer Res. 21, 1154 (1961).
H. Stähelin: Eur. J. Cancer 12, 925 (1976).
H. Schön: unpublished results.
B.P. Wiesner, J. Yudkin : Nature 176, 249 (1955).
U. Friederich: SAKK (Schweizerische Arbeitsgruppe für klinische Krebsforschung) Bulletin 3(3), 3 (1983).
R.S. Gupta, A. Bromke, D.W. Bryant, R. Gupa, B. Singh and D. R. McCalla: Mutagenesis 2, 179 (1987).
S.M. Sieber, J. Whang-Peng, C. Botkin and T. Knutsen: Teratology 18, 31 (1978).
D.M. DeMarini, K.H. Brock, C.L. Doerr and M.M. Moore: Mutat. Res. 187, 141 (1987).
T.L. Avery, D. Roberts and R.A. Rice: Cancer Chemothr. Rep., Part 1, 57, 165 (1973).
M. Hacker and D. Roberts: Cancer Res. 35, 1756 (1975).
M. Kalberer-Rüsch: unpublished results.
T. Lee and D. Roberts: Cancer Res. 44, 2981 (1984).
T. Lee and D. Roberts: Cancer Res. 44, 2986 (1984).
J.A. Moscow and K.H. Cowan: J. natl Cancer Inst. 80, 14 (1988).
R. A. Kramer, J. Hakher and G. Kim: Science 241, 694 (1988).
L.M. Slater, S.L. Murray, M.W. Wetzel, P. Sweet and M. Stupecky: Cancer Chemother. Pharmac. 16, 50 (1986).
S. Akiyama, N. Shiraishi, Y. Kuratomi, M. Nakagawa and M. Kuwano: J. natl Cancer Inst. 76, 839 (1986).
R. Osieka, S. Seeber, R. Pannenbäcker, D. Soll, P. Glatte and C. G. Schmidt: Cancer Chemother. Pharmac. 18, 198 (1986).
P.R. Twentyman, N.E. Fox and D.J.G. White: Br. J. Cancer 56, 55 (1987).
R.B. Lock and B.T. Hill: Intern. J. Cancer 42, 373 (1988).
Sandoz Ltd.: VP 16–213, Preclinical Brochure (1970).
M.K. Spigelman, R.A. Zappulla, J.A. Sträuchen, E.J. Feuer, J. Johnson, S.J. Goldsmith, L.I. Malis and J.F. Holland: Cancer, Res. 46, 1453 (1986).
H. Stähelin: Krebsinformation (Swiss Cancer League) 8 (3), 79 (1973).
H. Stähelin: Progr. Allergy 38, 19 (1986).
J. Franz: unpublished results.
G. Rüttimann: unpublished results.
O. Wagner: unpublished results.
A. Grieder: unpublished results (1971).
L.M. Allen: Cancer Res. 38, 2549 (1978); Drug Metab. Rev. 8, 119 (1978).
R. Bailey-Wood, C.M. Dallimore, T.J. Littlewood and D.P. Bentley: Br. J. Cancer 52, 613 (1985).
B.H. Long: Natl Cancer Inst. Monogr. 4, 123 (1987).
L.M. Allen and P.J. Creaven: Eur. J. Cancer 11, 697 (1975).
P.J. Creaven: In: B.F. Issell et al., ref. [1] p. 103, (1984).
W.E. Evans, J.A. Sinkule, P.R. Hutson, F.A. Hayes and G. Rivera: In: B.F. IsScil et al., ref. [1] p. 117, (1984).
M. D’Incalci and S. Garattini: In: Cancer Chemotherapy and Biological Response Modifiers, Annual 9, p. 67. Eds H.M. Pinedo, D.L. Longo and B.A. Chabner. Elsevier 1987.
M. D’Incalci and S. Garattini: In: Cancer Chemotherapy and Biological Response Modifiers, Annual 10, p. 57. Eds H.M. Pinedo, D.L. Longo and B.A. Chabner. Elsevier 1988.
K.H. Pflüger, L. Schmidt, M. Merkel, H. Jungclas and K. Havemann: Cancer Chemother. Pharmac. 20, 59 (1987).
M. D’ncalci, P. Farina, C. Sessa, C. Mangioni, V. Conter, G. Masera, M. Rocchetti, M. Brambilla Pisoni, E. Piazza, M. Beer and F. Cavalli: Cancer Chemother. Pharmac. 7, 141 (1982).
K. Hande, L. Anthony, R. Hamilton, R. Bennett, B. Sweetman and R. Branch: Cancer Res. 48, 1829 (1988).
F.M. Muggia: Proc. Am. Ass. Cancer Res. 11, 58 (1970).
G. Trempe, M. Sykes, C. Young and I. Krakoff: Proc. Am. Ass. Cancer Res. 11, 79 (1970).
F.M. Muggia, O.S. Selawry and H.H. Hansen: Cancer Chemother. Rep., part 1, 55, 575 (1971).
EORTC Clinical Screening Group: 7th Int. Congr. Chemother., Prague, Abstract B-8/11 (1971).
G. Mathe: Paris Match, 13 March (1971).
H. Limburg: Arch. Gynäk. 211, 384 (1971).
P. Dombernowsky, N.I. Nissen and V. Larsen: Cancer Chemother. Rep., part 1, 56, 71 (1972).
EORTC Co-operative Group: Br. med. J. 2, 744 (1972).
R.W. Sonntag, H.J. Senn, G. Nagel, K. Giger and P. Alberto: Eur. J. Cancer 10, 93 (1974).
M.A. Goldsmith and S.K. Carter: Eur. J. Cancer 9, 477 (1973).
M. Rozencweig, D.D. Von Hoff, J. E. Henney and F. M. Muggia: Cancer 40, 334 (1977).
P.J. O’Dwyer, M.T. Alonso, B. Leyland-Jones and S. Marsoni: Cancer Treatment Rep. 68, 1455 (1984).
J.L. Grem, D.F. Hoth, B. Leyland-Jones, S.A. King, R.S. Ungerleider and R.E. Wittes: J. clin. Oncol. 6, 351 (1988).
K.W. Brunner: Internal Report (1971).
N.I. Nissen, V. Larsen, H. Pedersen and K. Thomsen: Cancer Chemother. Rep., part 1, 56, 769 (1972).
EORTC, Clinical Screening Group: Br. med. J. 3, 199 (1973).
J.J. Wang and D.S. Chervinsky: Proc. Am. Ass. Cancer Res. 14, 110 (1973).
J.-L. Amiel, L. Schwarzenberg, M. Musset, F. de Vassal, M. Hayat and G. Mathe: Bull. Cancer 61, 419 (1974).
W.F. Jungi, H.J. Senn, C. Beckmann and P. Radielovic: Krebsinformation (Swiss Cancer League) 9 (2), 50 (1974).
K.W. Brunner, R.W. Sonntag, F. Cavalli and H. J. Ryssel: Krebsinformation (Swiss Cancer League) 9 (2), 49 (1974).
P.J. Creaven, S.J. Newman, O.S. Selawry, M.H. Cohen and A. Primack: Cancer Chemother. Rep., part 1, 58, 901 (1974).
G Falkson and H. Falkson: Proc. Am. Ass. Cancer Res. 15, 160 (1974).
S. Seeber, G.A. Nagel, W. Achterrath, C.G. Schmidt and R. Raettig, (Eds): Etoposid, In: Aktuelle Onkologie, vol. 4. W. Zuckschwerdt Verlag, München 1981.
J. Schwarzmeier, E. Deutsch and K. Karrer, (Eds): Etoposid (VP 16–213) in der Therapie maligner Erkrankungen. Springer-Verlag, Wien 1984.
J.A. Sinkule: Pharmacotherapy 4, 61 (1984).
P. J. O’Dwyer, B. Leyland-Jones, M. T. Alonso, S. Marsoni and R. E. Wittes: New Engl. J. Med. 312, 692 (1985).
R. Marsoni, D. Hoth, R. Simon, B. Leyland-Jones, M. De Rosa and R.E. Wittes: Cancer Treatment Rep. 71, 71 (1987).
F. Cavalli, A. Goldhirsch and R. Joss: In: B.F. Issell et al, ref. [1] (1984), p. 163.
F. Kung, F.A. Hayes, J. Krischer, D. Mahoney Jr., B. Leventhal, G. Brodeur, D. H. Berry, R. Dubowy and S. Toledano: Invest. New Drugs 6, 31 (1988).
L. Vellekoop, G. Spitzer, M. Keating, K. McCredie and E. Hersh: Proc. Am. Soc. Clin. Oncol. 21, 444 (1980).
S.N. Wolffand M.F. Fer: Proc. Am. Ass. Cancer Res. 25, 134 (1982).
N.H. Mulder, A.F. Meinesz, D.T. Sleijfer, P.E. Postmus, E.G.E. de Vries, C.T. Smit Sibinga and R. Vriesendorp: In: Autologous Bone Marrow Transplantation and Solid Tumors, Eds J.G. McVie, O. Dalesio and I.E. Smith. Raven Press, New York 1984.
R.A. Stahel, R.W. Takvorian, A.T. Skarin and G.P. Canellos: Eur. J. Cancer clin. Oncol. 20, 1233 (1984).
K. G. Blume, S. J. Forman, M. R. O’Donnell et al.: Blood 66 (suppl. 1), 883A (1985); Blood 69, 1015 (1987).
A.R. Zander, S. Culbert, S. Jagannath et al.: Cancer 59, 1083 (1987).
A Gratwohl, B. Osterwalder, A. Lori, C. Nissen and B. Speck: Exp. Hemat. 75 (suppl. 17), 11 (1985).
B Häfliger, A. Gratwohl, A. Tichelli, A. Würsch and B. Speck: Sem. Oncol. 14 (Suppl. 1), 134 (1987).
N. Ciobanu, E. Paietta, M. Andreeff, P. Papenhausen and P.H. Wiernik: Exp. Hemat. 14, 626 (1986).
A. De Fabritiis, A. Pulsoni, A. Sandrelli, F. Simone, S. Amadori, G. Meloni and F. Mandelli: Bone Marrow Transplant. 2, 287 (1987).
L. Wood and P. Jacobs: Am. J. Hemat. 27, 63 (1988).
J.A. Snyder and R.C. Mc Intosh: A. Rev. Biochem. 45, 699 (1976).
J.K. Kelleher: Molec. Pharmac. 13, 232 (1977); Cancer Treatm. Rep. 62, 1443 (1978).
J. D. Loike, C.F. Brewer, H. Sternlicht, W. J. Gensler and S. B. Horwitz : Cancer Res. 38, 2688 (1978).
H Stähelin and G. Poschmann: Oncology 35, 217 (1978).
A. Grieder, R. Maurer and H. Stähelin: Experientia 29, 112 (1973).
A. Grieder, R. Maurer and H. Stähelin: Cancer Res. 34, 1788 (1974).
N.C. Misra and D. Roberts: Cancer Res. 35, 99 (1975).
A. Krishan, K. Paika and E. Frei: J. Cell. Biol. 66, 521 (1975).
A P. Rao and P.N. Rao: J. Cell Biol. 67, 351a (1975); J. natl Cancer Inst. 57, 1139 (1976).
Barlogie and B. Drewinko: In: Pulse Cytophotometry, p. 226. Eds E. Göhde, J. Schumann and Th. Büchner. European Press, Ghent 1976.
B. Drewinko and B. Barlogie: Cancer Treatm. Rep. 60, 1295 (1976).
L. Wilson, J. R. Bamburg, S. B. Mizel, L. M. Grisham and K. M. Creswell: Fedn Proc. 33, 158 (1974).
P. Gradwohl and H. Stähelin: 10th Int. Cancer Congr., Houston (1970), abstract No. 644.
A. Grieder, R. Maurer and H. Stähelin: Cancer Res. 37, 2998 (1977).
J. Ostrowski: unpublished results (1970/71).
A. Grieder and R. Maurer: Experientia 30, 703 (1974).
J.A. Fontana: Cancer Treatm. Rep. 63, 224 (1979).
R.J. Giever, R.S. Heusinkveld, M.R. Manning and G.T. Bowden: Int. J. Radiat Oncol. Biol. Phys. 8, 921 (1981).
R.S. Gupta: Cancer Res. 43, 1568 (1983).
B.T. Hill and A.S. Bellamy: Int. J. Cancer 33, 599 (1984).
J.D. Loike and S.B. Horwitz: Biochemistry 15, 5435 (1976).
J.J. Wang and D.S. Chervinsky: Proc. Am. Ass. Cancer Res. 14, 110 (1973).
M. Gosalvez, J. Perez-Garcia and M. Lopez: Eur. J. Cancer 8, 471 (1972).
M. Gosalvez, M. Blanco, J. Hunter, M. Miko and B. Chance: Eur. J. Cancer 10, 567 (1974).
M. Gosalvez, R. Garcia-CaAero and H. Reinhold: Eur. J. Cancer 11, 709 (1975).
C.C. Huang, Y. Hou and J.J. Wang: Cancer Res. 33, 3123 (1973).
R.A. Tobey: Nature 254, 245 (1975).
J.D. Loike and S.B. Horwitz: Biochemistry 15, 5443 (1976).
D. Roberts, S. Hilliard and C. Peck: Cancer Res. 40, 4225 (1980).
A.M. Arnold and J.M.A. Whitehouse: Br. J. Cancer 43, 733 (1981).
A.J. Wozniak and W.R. Ross: Proc. Am. Ass. Cancer Res. 23, 197 (1982); Cancer Res. 43, 120 (1983).
D.K. Kalwinsky, A.T. Look, J. Ducore and A. Fridland: Cancer Res. 43, 1592 (1983).
B.H. Long and A. Minocha: Proc. Am. Ass. Cancer Res. 24, 321 (1983).
A. Minocha and B.H. Long: Biochem. biophys. Res. Commun. 122, 165 (1984).
B.H. Long and M.G. Brattain: In: B.F. Issell et al, ref. [1] p. 63, (1984).
G.L. Chen, L Yang, T.C. Rowe, B.D. Halligan, K.M. Tewey and L.F. Liu: J. biol. Chem. 259, 13560 (1984).
W. Ross, T. Rowe, B. Glisson, J. Yalowich and L. Liu: Cancer Res. 44, 5857 (1984).
B. Glisson, R. Gupta, S. Smallwood, E. Cantu and W. Ross: Proc. Am. Ass. Cancer Res. 26, 340 (1985).
T. Rowe, G. Kupfer and W. Ross: Biochem. Pharmac. 34, 2483 (1985).
L.F. Liu: Proc. Am. Ass. Cancer Res. 29, 524 (1988).
D. Kerrigan, Y. Pommier and K.W. Kohn: Natl Cancer Inst. Monogr. 4, 117 (1987).
B. Glisson, R. Gupta, S. Smallwood and W. Ross: Cancer Res. 46, 1934 (1986).
M. Potmesil and W.E. Ross (eds): Natl. Cancer Inst. Monogr. 4, several articles (1987).
J.A. Moscow and K.H. Cowan: J. natl Cancer Inst. 80, 14 (1988).
B. K. Sinha, N. Haim, L. Dusre, D. Kerrigan and Y. Pommier: Cancer Res. 48, 5096 (1988).
B. H. Long, S. T. Musial and M. G. Brattain: Cancer Res. 45, 3106 (1985).
B. H. Long, S. T. Musial and M. G. Brattain: Cancer Res. 46, 3809 (1986).
J.M. Woynarowski, R.D. Sigmund and T.A. Beerman: Biochim. biophys. Acta 950, 21 (1988).
J.M. Woynarowski, R.D. Sigmund and T.A. Beerman: Proc. Am. Ass. Cancer Res. 29, 274 (1988).
J Markovits, Y. Pommier, D. Kerrigan, J.M. Covey, E.J. Tilchen and K.W. Kohn: Cancer Res. 47, 2050 (1987).
W. G. Nelson, K. R. Cho, Y. Hsiang, L. F. Liu and D. S. Coffey: Cancer Res. 47, 3246 (1987).
D. M. Sullivan, M. D. Lathan and W. E. Ross: Cancer Res. 47, 3973 (1987).
K. Chow and W.E. Ross: Molec. cell. Biol. 7, 3119 (1987).
K. Chow, C.K. King and W.E. Ross: Biochem. Pharmac. 37, 1117 (1988).
M. Bakic, D. Chan, B.S. Andersson, M. Beran, L. Silberman, E. Estey, L. Ricketts and L.A. Zwelling: Biochem. Pharmac. 36, 4067 (1987).
J. Hwang, J. Whang, S. Shyy, L.F. Liu: Proc. Am. Ass. Cancer Res. 29, 324 (1988).
W.D. Henner and M.E. Blazka: J. natl Cancer Inst. 76, 1007 (1986).
P. J. Smith, C. O. Anderson and J. V. Watson: Cancer Res. 46, 5641 (1986).
B.K. Sinha, M.A. Trush and B. Kalyanaraman: Biochem. Pharmac. 52, 3495 (1983).
J.M.S. van Maanen, C. de Ruiter, P.R. Kootstra, M.V. Lafleur, J. De Vries, J. Retil and H.M. Pinedo: Eur. J. Cancer clin. Oncol. 21, 1215 (1985).
B.K. Sinha, M.A. Trush and B. Kalyanaraman: Biochem. Pharmac. 34, 2036 (1985).
J.M.S. van Maanen, J. De Vries, D. Pappie, E. van den Akker, M.V.M. Lafleur, J. Retil, J. van der Greef and H.M. Pinedo: Cancer Res. 47, 4658 (1987).
N. Haim, J. Nemec, J. Roman and B.K. Sinha: Cancer Res. 47, 5835 (1987).
J.M.S. van Maanen, U.H. Verkerk, J. Broersen, M.V.M. Lafleur, J. De Vries, J. Retfcl and H.M. Pinedo: Free Rad. Res. Commun. 4, 371 (1988).
H.H.J.L. Ploegmakers and W.J. van Oort: J. autom. Chem. 10, 135 (1988).
B.A. Teicher, S.A. Holden and C.M. Ross: J. natl. Cancer Inst. 75, 1129 (1985).
M. Broggini, C. Rossi, E. Benfenati, M. D’ncalci, R. Fanelli and P. Gariboldi: Chem.-Biol. Interactions 55, 215 (1985).
W.E. Ross: Proc. Am. Ass. Cancer Res. 29, 535 (1988).
I. Jardine: In: Anticancer Agents Based on Natural Product Models, p. 319. Eds J. Cassady and J. Douros. Academic Press, Orlando 1980.
B. H. Long, S. T. Musial and M. G. Brattain: Biochemistry 23, 1183 (1984).
R. S. Gupta, P. C. Chenchaiah and R. Gupta: Anti-Cancer Drug Design 2, 1 (1987).
J.D. Griffiths, R.J. Stark, J.C. Ding and I.A. Cooper: Cancer Treatm. Rep. 70, 519 (1986).
R.S. Gupta: Cancer Res. 43, 505 (1983).
R.S. Gupta and B. Singh: J. natl Cancer Inst. 73, 241 (1984).
L.S. Thurston, H. Irie, S. Tani, F. Han, Z. Liu, Y. Cheng and K. Lee: J. med. Chem. 29, 1547 (1986).
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Stähelin, H., von Wartburg, A. (1989). From podophyllotoxin glucoside to etoposide. In: Jucker, E. (eds) Progress in Drug Research. Progress in Drug Research, vol 33. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9146-2_8
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