Abstract
The proton conductance of the inner membrane of hamster brown adipose tissue mitochondria can be regulated in vitro by exogenous purine nucleotides, which “bind to a component on the outer face of the inner membrane. This unique mechanism has been proposed to represent the molecular site of non-shivering thermogenesis in this tissue. Using a photo-affinity analogue of ATP, we have identified the nucleotide binding component as a protein of 32,000 daltons.
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Nicholls, D.G., Bernson, V.S.M., Heaton, G.M. (1978). The Identification of the Component in the Inner Membrane of Brown Adipose Tissue Mitochondria Responsible for Regulating Energy Dissipation. In: Girardier, L., Seydoux, J. (eds) Effectors of Thermogenesis. Experientia Supplementum, vol 32. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5559-4_9
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DOI: https://doi.org/10.1007/978-3-0348-5559-4_9
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-5561-7
Online ISBN: 978-3-0348-5559-4
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