Abstract
The inability to measure mechanical forces within cells has been limiting our understanding of how mechanical information is processed on the molecular level. In this chapter, we describe a method that allows the analysis of force propagation across distinct proteins within living cells using Förster resonance energy transfer (FRET)-based biosensors.
Katharina Austen, Carleen Kluger, and Andrea Freikamp have contributed equally to this chapter.
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Austen, K., Kluger, C., Freikamp, A., Chrostek-Grashoff, A., Grashoff, C. (2013). Generation and Analysis of Biosensors to Measure Mechanical Forces Within Cells. In: Baudino, T. (eds) Cell-Cell Interactions. Methods in Molecular Biology, vol 1066. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-604-7_15
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DOI: https://doi.org/10.1007/978-1-62703-604-7_15
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Publisher Name: Humana Press, Totowa, NJ
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