Abstract
The Wnt/planar cell polarity (PCP) signaling pathway plays a critical role in wing, eye, neural tube defects, and sensory bristle development of Drosophila and vertebrate development. Recently, the Wnt/PCP pathway has been known to regulate convergent extension (CE) movements that are essential for establishing the three germ layers and body axis during early vertebrate development. Here, we describe detailed practical procedures required for the particular studies in Xenopus CE movements
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Acknowledgments
We acknowledge Mi-Jung Kim and other members of our laboratory for reading this manuscript and providing constructive criticism. This work was supported by the National Research Foundation of Korea (KRF) grant (No. 20090092829) and K-MeP project (T31130) of Korea Basic Science Institute (KBSI).
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Kim, GH., Park, E.C., Han, JK. (2012). Wnt/Planar Cell Polarity Signaling in the Regulation of Convergent Extension Movements During Xenopus Gastrulation. In: Turksen, K. (eds) Planar Cell Polarity. Methods in Molecular Biology, vol 839. Springer, New York, NY. https://doi.org/10.1007/978-1-61779-510-7_7
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DOI: https://doi.org/10.1007/978-1-61779-510-7_7
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