Abstract
Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a new technology to map protein–DNA interactions in a genome. The genome-wide transcription factor binding site and chromatin modification data produced by ChIP-seq provide invaluable information for studying gene regulation. This chapter reviews basic characteristics of ChIP-seq data and introduces a computational procedure to identify protein–DNA interactions from ChIP-seq experiments.
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Ji, H. (2010). Computational Analysis of ChIP-seq Data. In: Ladunga, I. (eds) Computational Biology of Transcription Factor Binding. Methods in Molecular Biology, vol 674. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-854-6_9
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DOI: https://doi.org/10.1007/978-1-60761-854-6_9
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