Abstract
Cancer is a genetic disease in which malignant cells have undergone mutations and epigenetic changes but maintain the transformed phenotype even when cultured or when injected into immunologically tolerant experimental animals (1,2). However, most of the genetic events in tumors are somatic (i.e., not hereditary), brought about environmentally or randomly, and the identified inherited (often referred to as “genetic”) causes account for a small proportion of all cancers.
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Hemminki, A., Hemminki, K. (2005). The Genetic Basis of Cancer. In: Curiel, D.T., Douglas, J.T. (eds) Cancer Gene Therapy. Contemporary Cancer Research. Humana Press. https://doi.org/10.1007/978-1-59259-785-7_2
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DOI: https://doi.org/10.1007/978-1-59259-785-7_2
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