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Neuropathology of Alzheimer’s Disease

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Alzheimer’s Disease

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative and dementing disorder that can be detected clinically only in its end phase. AD is the most widespread type of dementia and affects about 10% of individuals older than 65 years and about 40% of individuals older than 80 years of age (1,2). The earliest sign of AD is a subtle decline in memory functions in a state of clear consciousness. Mental capabilities gradually worsen and personality changes appear, followed by deterioration of language functions, impairment of visuospatial tasks, and, in the disease’s final stages, dysfunction of the motor system in the form of a hypokinetic-hypertonic syndrome.

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Authors
  1. Christian Schultz
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  2. Kelly Del Tredici
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  3. Heiko Braak
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Editor information

Editors and Affiliations

  1. The University of Oklahoma College of Medicine, USA

    Ralph W. Richter MD, FACP (Clinical Professor of Neurology and Psychiatry, Director) (Clinical Professor of Neurology and Psychiatry, Director)

  2. Alzheimer’s Disease Research Unit, St. John Medical Center, Tulsa, OK, USA

    Ralph W. Richter MD, FACP (Clinical Professor of Neurology and Psychiatry, Director) (Clinical Professor of Neurology and Psychiatry, Director)

  3. Tulsa, OK, USA

    Brigitte Zoeller Richter DiplPharm (Pharmacist, Publicist) (Pharmacist, Publicist)

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Schultz, C., Del Tredici, K., Braak, H. (2004). Neuropathology of Alzheimer’s Disease. In: Richter, R.W., Richter, B.Z. (eds) Alzheimer’s Disease. Current Clinical Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-661-4_2

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  • DOI: https://doi.org/10.1007/978-1-59259-661-4_2

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-4485-9

  • Online ISBN: 978-1-59259-661-4

  • eBook Packages: Springer Book Archive

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