Abstract
Diabetic foot ulcers occur as a common complication of diabetes. Healing of the ulcers is largely delayed by the concomitant infection. Antibiotic treatment of infected ulcers is complicated by formation of microbial biofilms , which are often heterogeneous and resistant to antibiotics. Bacteriophage therapy is considered as an additional approach to the treatment of infected wounds. Here, we describe the basic method of application of bacteriophages for treatment of infected diabetic foot ulcers, including ones that are very large.
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Acknowledgement
This study was supported by the Russian Ministry of Education and Science, Project 0309-2016-0002 and the Program of Russian Academy of Sciences “Basic researches for development of medical technologies,” Project No. 2014-155.
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Morozova, V.V., Kozlova, Y.N., Ganichev, D.A., Tikunova, N.V. (2018). Bacteriophage Treatment of Infected Diabetic Foot Ulcers. In: Azeredo, J., Sillankorva, S. (eds) Bacteriophage Therapy. Methods in Molecular Biology, vol 1693. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7395-8_13
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DOI: https://doi.org/10.1007/978-1-4939-7395-8_13
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Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-7394-1
Online ISBN: 978-1-4939-7395-8
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