Abstract
Nuclear magnetic resonance (NMR) spectroscopy techniques allow the acquisition of a large amount of data and when combined with multivariate statistical analysis, it is possible to process and interpret the obtained NMR data in accordance with the biological problem being investigated. In this chapter, the search for biologically relevant biomarkers is addressed using NMR spectroscopy-based metabolomics, due to their clinical relevance for either diagnosis or monitoring of diseases and disorders.
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Acknowledgments
We thank the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, São Paulo, Brazil) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brasília, Brazil) for financial supports (FAPESP Process No 2014/18938-8 and CNPq Process Number: 454234/2014-7) and fellowships.
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Pontes, J.G.M., Brasil, A.J.M., Cruz, G.C.F., de Souza, R.N., Tasic, L. (2017). 1H NMR Metabolomic Profiling of Human and Animal Blood Serum Samples. In: Guest, P.C. (eds) Multiplex Biomarker Techniques. Methods in Molecular Biology, vol 1546. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-6730-8_24
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DOI: https://doi.org/10.1007/978-1-4939-6730-8_24
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