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The Insula of Reil in Man and Monkey

Architectonics, Connectivity, and Function

  • Chapter
Association and Auditory Cortices

Part of the book series: Cerebral Cortex ((CECO,volume 4))

Abstract

During the fetal stages of primate development, the insula is situated on the surface of the cerebral hemisphere (Fig. 1A). However, in the more advanced primates, the adjacent neocortical areas develop much more extensively than the insula. This leads to massive frontal, parietal, and temporal opercularization and to the formation of the sylvian fissure within which the insula remains buried from the time of birth onwards. In subprimate mammalian species where the neocortex does not develop as extensively, the homolog of the insula remains exposed on the surface of the brain throughout adult life (Rose, 1928).

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Authors and Affiliations

  1. Bullard and Denny-Brown Laboratories and Behavioral Neurology Section, Neurology Department, Harvard University, Boston, Massachusetts, 02215, USA

    M.-Marsel Mesulam & Elliott J. Mufson

  2. Charles A. Dana Research Institute, Beth Israel Hospital, Boston, Massachusetts, 02215, USA

    M.-Marsel Mesulam & Elliott J. Mufson

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  1. M.-Marsel Mesulam
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  1. Boston University School of Medicine, Boston, Massachusetts, USA

    Alan Peters

  2. California College of Medicine, University of California, Irvine, Irvine, California, USA

    Edward G. Jones

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Mesulam, MM., Mufson, E.J. (1985). The Insula of Reil in Man and Monkey. In: Peters, A., Jones, E.G. (eds) Association and Auditory Cortices. Cerebral Cortex, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9619-3_5

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