Abstract
Presently the most commonly used anticoagulant drug for protein C (PC) deficiency is coumadin. This oral anticoagulant acts by inhibiting the action of vitamin K, which in turn inhibits the activity of coagulation proteins Factor V and Factor VIII. Though often used for long-term therapy, coumadin is also likely to cause complications such as minor to persistent bleeding, sensitivity reactions, and in more severe cases, skin necrosis. It has also been suggested that long-term use of this oral anticoagulant could lead to tissue and organ damage.
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Thiessen, E.E., Bruley, D.F. (2003). Theoretical Studies of IMAC Interfacial Phenomena for the Production of Protein C. In: Thorniley, M., Harrison, D.K., James, P.E. (eds) Oxygen Transport to Tissue XXV. Advances in Experimental Medicine and Biology, vol 540. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6125-2_26
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DOI: https://doi.org/10.1007/978-1-4757-6125-2_26
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