Abstract
The pharmacology of taurine has received close study, and taurine has been shown to be beneficial in conditions as diverse as genetic cardiomyopathy (1), cardiac arrhythmias (2), and epilepsy (5). Deficiencies in taurine have also been associated with the development of such pathological processes as retinal degeneration in cats (9) and cardiomyopathy in humans (4). These investigations have linked taurine with various phenomena without yielding insight into the mechanism by which taurine is acting, or its normal functional involvement in cellular processes.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Azari, J., Brumbaugh, P., and Huxtable, R., 1980, Prophylaxis by taurine in the hearts of cardiomyopathie hamsters, J. Mol. Cell. Cardiol, 12: 1353–1366.
Chazov, E., Mal’Chikova, L., Lipina, N., Reshetnaya, N., Asafoy, G., and Smirnov, V., 1974, Taurine effect on the electrical activity of the heart, Kardiologiya 14 (7): 18–26.
Collins, G.G.S., 1974, The rates of synthesis, uptake, and disappearance of (14C) taurine in eight areas of the rat central nervous system, Brain Res, 76: 447–458.
Darsee, J.R., and Heymsfield, S.B., 1981, Decreased myocardial taurine levels and hypertaurinuria in a kindred with mitral valve prolapse and congestive cardiomyopathy, New Eng. J. Med, 304; 129–135.
Huxtable, R., and Laird, H., 1978, The prolonged anticonvulsant action of taurine on genetically determined seizure susceptibility, Can. J. Neurol. Sci, 5: 215–221.
Kaczmarek, L.K., A comparison of the evidence for taurine and GABA as neurotransmitters, in: “Taurine,” R. Huxtable and A. Barbeau, eds., Raven Press, New York (1976), pp. 283–292
Kibe, C., Wake, C., Kuramoto, T., and Hoshita, T., 1980, Effect of dietary taurine on bile acid metabolism in guinea pigs, Lipids, 15: 224–229.
National Academy of Sciences: Nutrient Requirements of Domestic Animals, Washington, D.C., (1978).
Schmidt, S.Y., Berson, E.L., Hayes, K.C., 1976, Retinal degeneration in cats fed casein 1. Taurine deficiency, Invest. Ophthalmol, 15: 47–52.
Sturman, J.A., 1973, Taurine pool sizes in the rat: Effects of vitamin B-6 deficiency and high taurine diet, J. Nutrition, 103 (11): 1566–1580.
Sturman, J.A., 1979, Taurine in developing rat brain: Changes in blood-brain barrier, J. Neurochem, 32: 811–816.
Sturman, J.A., Rassin, D.K., and Gaull, G.E., 1977, Taurine in developing rat brain: Transfer of (35S) taurine to pups via the milk, Pediat. Res, 11: 28–33.
Sturman, J.A., Rassin, D.K., and Gaull, G.E., 1977b, Taurine in developing rat brain: Maternal-fetal transfer of (35S) taurine and its fate in thè neonate, J. Neurochem, 28: 31–39.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Plenum Press, New York
About this chapter
Cite this chapter
Huxtable, R.J., Lippincott, S.E. (1982). Sources and Turnover Rates of Taurine in Newborn, Weanling, and Mature Rats. In: Huxtable, R.J., Pasantes-Morales, H. (eds) Taurine in Nutrition and Neurology. Advances in Experimental Medicine and Biology, vol 139. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0402-0_2
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0402-0_2
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-0404-4
Online ISBN: 978-1-4757-0402-0
eBook Packages: Springer Book Archive