Skip to main content
SpringerLink
Log in

Dementia of the Alzheimer Type Recapitulates Ontogeny Inversely on Specific Ordinal and Temporal Parameters

  • Chapter
Neurodevelopment, Aging and Cognition

Abstract

The phenomenology of Alzheimer’s disease (AD) has been described in increasing detail over the past decade. These increasingly detailed descriptions of the evolution of AD have manifest diagnostic, prognostic, and management importance. Additionally, striking homologies between normal human development and the degenerative course of AD are now apparent. These homologies may be more than fortuitous. Accordingly, it is reasonable at this time to speculate that the course of AD may result directly or indirectly from the disruption of CNS developmental factors and/or processes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Adams F, ed. (1861): The Extant Works of Aretaeus, the Cappadoccian. London: Syndenham Society

    Google Scholar 

  • Aletta JM, Lewis SA, Cowan NJ, Greene LA (1988): Nerve growth factor regulates both the phosphorylation and steady-state levels of microtubule-associated protein 1.2 (MAP1.2). J Cell Biol 106:1573–1581

    Article  Google Scholar 

  • Alford BB, Bogle ML (1982): Nutrition during the Life Cycle. Englewood Cliffs, NJ: Prentice-Hall

    Google Scholar 

  • American Psychiatric Association (1980): Diagnostic and Statistical Manual of Mental Disorders, 3rd Edition. Washington, DC: American Psychiatric Association

    Google Scholar 

  • Aristophanes (423 BC): Clouds, translated by Thomas Mitchell [1783-1845]. Cited in: Familiar Quotations, Bartlett J, 13th ed. (1955), Little, Brown and Co., p. 23

    Google Scholar 

  • Borenstein J, Reisberg B (1987): Functional deficits in Alzheimer’s disease. 1987 New Research Program and Abstracts. American Psychiatric Association, 140th Annual Meeting, 56 (Abstract)

    Google Scholar 

  • Broderick P, Laszlo JI (1987): The drawing of squares and diamonds: A perceptual-motor task analysis. J Exper Child Psychol 43:44–61

    Article  Google Scholar 

  • Brugg B, Matus A (1988): PC12 cells express juvenile microtubule-associated proteins during nerve growth factor-induced neurite outgrowth. J Cell Biol 107:643–650

    Article  Google Scholar 

  • Chen MJ (1985): Young children’s representational drawings of solid objects: A comparison of drawings and copying. In: Visual Order, Freedman NH, Cox MV, eds. New York: Cambridge University Press

    Google Scholar 

  • Cole MG, Dastoor D (1980): Development of a dementia rating scale: Preliminary communication. J Clin Exp Gerontol 2:46–63

    Google Scholar 

  • Cole MG, Dastoor DP (1987): A new hierarchic approach to the measurement of dementia. Psychosomatics 28:298–304

    Article  Google Scholar 

  • Cole MG, Dastoor DP, Koszycki D (1983): The hierarchic dementia scale. J Clin Exp Gerontol 5:219–234

    Google Scholar 

  • Constantinidis J, Richard J, de Ajuriaguerra J (1978): Dementias with senile plaques and neurofibrillary changes. In: Studies in Geriatric Psychiatry, Isaacs AD, Post F, eds. New York: John Wiley, pp. 119–152

    Google Scholar 

  • Cox MV (1986): Cubes are difficult things to draw. British Journal of Developmental Psychology 4:341–345

    Article  Google Scholar 

  • Cratty BJ (1986): Perceptual and Motor Development in Infants and Young Children. Macmillan, New York

    Google Scholar 

  • de Ajuriaguerra J, Rey M, Bellet-Muller M (1964): A propos de quelques problemes posées par le deficit opératoire de viellards atteints de démence degenerative en debut D’évolution. Cortex 1:232–256

    Google Scholar 

  • de Ajuriaguerra J, Tissot R (1968): Some aspects of psychoneurologic disintegration in senile dementia. In: Senile Dementia, Mueller CH, Ciompi L, eds. Switzerland: Huber, pp. 67–79

    Google Scholar 

  • de Ajuriaguerra J, Tissot R (1975): Some aspects of language in various forms of senile dementia: Comparisons with language in childhood. In: Foundations of Language Development, Vol 1. Lennenberg EH, Lennenberg E, eds. New York: Academic Press

    Google Scholar 

  • de Leon MJ, McRae T, George AE, Marcus D, Freedman M, Wolf AP, McEwen B (1988) Abnormal Cortisol response in Alzheimer’s disease with CT and PET temporal lobe changes. Lancet 2(8607): 391–392

    Article  Google Scholar 

  • Dunst C (1980): A Clinical and Educational Manual for Use with the Uzgiris and Hunt Scales of Infant Psychological Development. Austin: Pro-Ed Pubs., Inc.

    Google Scholar 

  • Eisenberg L (1975): Normal child development. In: Comprehensive Textbook of Psychiatry II, Vol 2. Freedman AM, Kaplan HR, Sadock BJ, eds. Baltimore: Williams and Wilkins, pp. 2036–2054

    Google Scholar 

  • Franssen EH, Reisberg B, Kluger A, Sinaiko E, Boja C (1991): Cognition independent neurologic symptomology in normal aging and probable Alzheimer’s disease. Archives of Neurology, 48:148–154

    Article  Google Scholar 

  • Galen (1821-1833 translation): De symptomatum différends liber. In: Opera Omnia, Kuhn CG, ed. Leipzig: Knobloch, pp. 200–201

    Google Scholar 

  • Gassier J (1984): A Guide to the Psychomotor Development of the Child. New York: Churchill Livingstone

    Google Scholar 

  • Gesell AL (1940): The First Five Years of Life; A Guide to the Study of the Preschool Child, from the Yale Clinic of Child Development. New York: Harper Bros

    Google Scholar 

  • Gesell AL, Ilg FL (1943): Infant and Child in the Culture of Today. New York: Harper Bros, pp. 141–245

    Google Scholar 

  • Grand RJ, ed. (1987): Pediatric Nutrition: Theory and Practice. Boston: Butter-worth

    Google Scholar 

  • Hefti F, Mash DC (1989): Localization of nerve growth factor receptors in the normal human brain and in Alzheimer’s disease. Neurobiology of Aging 10:75–87

    Article  Google Scholar 

  • Hughes CP, Berg L, Danziger WL, Cohen LA, Martin RL (1982): A new clinical scale for the staging of dementia. Br J Psychiatry 140:566–572

    Article  Google Scholar 

  • Hurlock EB (1978): Child Development, 6th ed. New York: McGraw-Hill

    Google Scholar 

  • Illingworth RS (1983): The Development of the Infant and Young Child: Normal and Abnormal. Edingburgh: Churchill Livingstone

    Google Scholar 

  • Illingworth RS (1987): The Normal Child. Some Problems of the Early Years and Their Treatment. Edinburgh: Churchill Livingstone

    Google Scholar 

  • King LS (1963): The Growth of Medical Thought. Chicago: University of Chicago Press

    Google Scholar 

  • Leeds M (1960): Senile recession: A clinical entity? J of the Am Ger Soc 8:122–131

    Google Scholar 

  • Leonard DGB, Gorham JD, Cole P, Greene LA, Ziff EB (1988): A nerve growth factor regulated messenger RNA encodes a new intermediate filament protein. J Cell Biol 106:181–193

    Article  Google Scholar 

  • Lin L-FH, Mismer D, Lile JD, Armes LG, Butler ET, Vannice JL, Collins F (1989): Purification, cloning, and expression of ciliary neurotrophic factor (CNTF). Science 246:1023–1025

    Article  Google Scholar 

  • Linden M (1957): Regression and recession in the psychoses of the aging. In: The Kirkpatrick Memorial Programs on Gerontology for 1955 and 1956, pp. 35–37

    Google Scholar 

  • Linden M, Courtney D (1953): The human life cycle and its interruptions. A psychologic hypothesis. Studies in gérontologie human relations I. Am J Psychiatry 109:906–915

    Google Scholar 

  • Lipowski ZJ (1980): Organic mental disorders: Introduction and review of syndromes. In: Comprehensive Textbook of Psychiatry, Vol. 2, Kaplan HI, Freed-Man AM, Sadock BJ, eds. Baltimore: Williams and Wilkins, pp. 1359–1392

    Google Scholar 

  • Lowrey GH (1978): Growth and Development of Children, 7th ed. Chicago: Year Book Medical Publishers

    Google Scholar 

  • Mitchelmore MG (1978): Developmental stages in children’s representation of regular solid figures. J Genet Psychol 133:229–239

    Google Scholar 

  • Mohs R, Kim G, Johns C, Dunn D, Davis K (1986): Assessing changes in Alzheimer’s disease: Memory and language. In: Handbook for Clinical Memory Assessment, Poon LW, ed. Washington, DC: American Psychological Association, pp. 149–155

    Chapter  Google Scholar 

  • Nelms BC (1982): Growth and Development: A Primary Health Care Approach. Englewood Cliffs, NJ: Prentice-Hall

    Google Scholar 

  • Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S (1982): Measurement of functional activities in older adults in the community. J Gerontol 37:323–329

    Google Scholar 

  • Phelps CH, Gage FH, Growdon JH, Hefti F, Harbaugh R, Johnston MV, Khacha-Turian ZS, Mobley WC, Price DL, Raskind M, Simpkins J, Thal LJ, Woodcock J (1989): Potential use of nerve growth factor to treat Alzheimer’s disease. Science 243:11

    Google Scholar 

  • Piaget J (1952): The Origins of Intelligence in Children. London: Routledge and Kegan Paul

    Book  Google Scholar 

  • Piaget J (1960): The Psychology of Intelligence. Totowa (NJ): Littlefield, Adams and Co

    Google Scholar 

  • Piaget J (1970): Genetic Epistemology. New York: Columbia University Press

    Google Scholar 

  • Piaget J (1973): The Child and Reality: Problems of Genetic Psychology. New York: Grossman Pub

    Google Scholar 

  • Piaget J Inhelder B (1956): The Child’s Conception of Space. London: Routledge and Kegan Paul

    Google Scholar 

  • Pierce CM (1975) Enuresis and encopresis. In: Comprehensive Textbook of Psychiatry II, Vol. 2, Freedman AM, Kaplan HR, Sadock BJ, eds. Baltimore: Williams and Wilkins, pp. 2116–2125

    Google Scholar 

  • Pipes PL (1981): Nutrition in Infancy and Childhood, 2nd ed. St. Louis: CV Mosby Co

    Google Scholar 

  • Plato (1921): The Laws (ed. trans.), Book IX. Manchester University Press

    Google Scholar 

  • Plutarch (1967): Lives North T, trans. New York: AMS Press

    Google Scholar 

  • Reisberg B (1986): Dementia: A systematic approach to identifying reversible causes. Geriatrics 41:30–46

    Google Scholar 

  • Reisberg B (1988): Functional assessment staging (FAST). Psychopharmacology Bulletin 24:653–659

    Google Scholar 

  • Reisberg B, Ferris SH, Anand R, de Leon M J, Schneck MK, Buttinger C, Boren-Stein J (1984): Functional staging of dementia of the Alzheimer’s type Ann NY Acad Sci 435:481–483

    Article  Google Scholar 

  • Reisberg B, Ferris SH, de Leon MJ, Crook T (1982): The global deterioration scale for assessment of primary degenerative dementia. Am J of Psychiatry 139:1136–1139

    Google Scholar 

  • Reisberg B, Ferris SH, de Leon MJ (1985): Senile dementia of the Alzheimer type: Diagnostic and differential diagnostic features with special reference to functional assessment staging. In: Senile Dementia of the Alzheimer Type, Vol. 2, Traber J, Gispen WH, eds. Berlin: Springer-Verlag, pp. 18–37

    Chapter  Google Scholar 

  • Reisberg B, Ferris SH, Franssen E (1986): Functional degenerative stages in dementia of the Alzheimer’s type appear to reverse normal human development. In: Biological Psychiatry, 1985, Vol 7, Shagass C et al., eds. New York: Elsevier Science Publishing Co, pp. 1319–1321

    Google Scholar 

  • Reisberg B, London E, Ferris SH, Borenstein J, Scheier L, de Leon MJ (1983b): The Brief Cognitive Rating Scale: Language, motoric, and mood concomitants in primary degenerative dementia. Psychopharmacology Bulletin 19:702–708

    Google Scholar 

  • Reisberg B, Schneck MK, Ferris SH, Schwartz GE, de Leon MJ (1983a): The brief cognitive rating scale (BCRS): Findings in primary degenerative dementia (PDD). Psychopharmacology Bulletin 19:47–50

    Google Scholar 

  • Rosenberg MB, Friedman T, Robertson RC, Tuszynski M, Wolff JA, Breakefield XO, Gage FH (1988): Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science 242:1575–1578

    Article  Google Scholar 

  • Rush B (1793): An account of the state of mind and body in old age. In: Medical Inquiries and Observations, Vol. 2, Philadelphia: Dobson, p. 311

    Google Scholar 

  • Sclan SG, Foster JR, Reisberg B, Franssen E, Welkowitz J (1990): Application of Piagetian measures of cognition in severe Alzheimer’s disease. The Psychiatric Journal of the University of Ottawa 15:223–228

    Google Scholar 

  • Simko MD, Cowell C, Hetza MS (1989): A Quick Reference for the Health Care Practitioner. Rockville, Maryland: Aspen Publishers, Inc.

    Google Scholar 

  • Torack RM (1983): The early history of senile dementia. In: Alzheimers Disease, Reisberg B, ed. New York: Free Press, Macmillan, pp. 23–28

    Google Scholar 

  • Uzgiris I, Hunt JMcV (1975): Assessment in Infancy: Ordinal Scales of Psychological Development. Urbana: University of Illinois

    Google Scholar 

  • Vaughn VC (1969): Growth and development. In: Textbook of Pediatrics, 9th ed. Nelson WE, Vaughn VC, McKay RJ, eds. Philadelphia: Saunders, pp. 15–57

    Google Scholar 

  • Wilson R, Kaszniak A (1986): Longitudinal changes: Progressive idiopathic dementia. In: Handbook for Clinical Memory Assessment, Poon LW, ed. Washington, DC: American Psychological Association, pp. 285–293

    Chapter  Google Scholar 

Download references

Authors
  1. Barry Reisberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Angela Pattschull-Furlan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Emile Franssen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Steven G. Sclan
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Alan Kluger
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Louis Dingcong
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Steven H. Ferris
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Dept. of Anatomy, University of Zagreb School of Medicine, 41000, Zagreb, Croatia

    Ivica Kostović

  2. Dept. of Neurology, University of Zagreb University Hospital Rebro, 41000, Zagreb, Croatia

    Stevo Knežević

  3. NYS Institute for Basic Research in Developmental Disabilities, Staten Island, NY, 10314, USA

    Henryk M. Wisniewski

  4. Dept. of Psychology, Washington College, Chestertown, MD, 21620, USA

    George J. Spilich

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Birkhäuser Boston

About this chapter

Cite this chapter

Reisberg, B. et al. (1992). Dementia of the Alzheimer Type Recapitulates Ontogeny Inversely on Specific Ordinal and Temporal Parameters. In: Kostović, I., Knežević, S., Wisniewski, H.M., Spilich, G.J. (eds) Neurodevelopment, Aging and Cognition. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6805-2_21

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-6805-2_21

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4684-6807-6

  • Online ISBN: 978-1-4684-6805-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation