Skip to main content

The Oxygen Dependency of the Redox State of Heme and Copper in Cytochrome Oxidase In Vitro

  • Chapter
Oxygen Transport to Tissue XI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 248))

Abstract

Near infrared spectrophotometry has been proposed as a tool for noninvasive evaluation of the metabolic processes in living tissue. With this technique, it is possible to monitor the tissue blood content, hemoglobin saturation level, and the redox state of copper in cytochrome oxidase. The redox behaviour of heme a+a3 in cytochrome oxidase and its use as an indicator of tissue oxygenation under low oxygen concentrations has already been studied by Oshino et al. (1974) However, there have been few studies upon the redox behaviour of copper under low oxygen concentrations corresponding to some mitochondrial energy states.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Bergersen, F.J. and Turner, G.L., 1979, Systems utilizing oxygenated leghemoglobin and myoglobin as a source of free dissolved CL at low concentrations for experiments with bacteria. Anal. Biochem., 96: 165.

    Article  PubMed  CAS  Google Scholar 

  • Jöbsis, F.F., 1977, Non invasive, infrared, monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science, 198: 1264.

    Article  PubMed  Google Scholar 

  • Kagawa,Y., 1979, Oxidative phosphorylation, in: Energy metabolisms and biological oxidations, Naoki, A, ed., Tokyo Kagaku Dojin, Toko.

    Google Scholar 

  • Lindsay, J.G. and Wilson, D.F., 1972, Apparent adenosine triphosphate induced ligand changes in cytochrome a3 of pigeon heart mitochondria. Biochemistry, 11: 4613.

    Article  PubMed  CAS  Google Scholar 

  • Oshino, N., Sugano, T., Oshino, R., and Chance, B., 1974, Mitochondrial function under hypoxic conditions: The steady states of cytochrome a+a3 and their relation to mitochondrial energy state. Biochem. Biophys. Acta., 368:298.

    Article  PubMed  CAS  Google Scholar 

  • Tamura, M., Oshino, N., Chance, B., and Silver, A.I., 1978, Optical measurements of intracellular oxygen concentration of rat heart in vitro. Arch. Biochem. Biophys., 191: 8.

    Article  PubMed  CAS  Google Scholar 

  • Wittenberg, J.B., Appleby, C.A., and Wittenberg, B.A., 1972, The kinetics of the reaction of leghemoglobin with oxygen and carbon monoxide. J. Biol. Chem., 247: 527.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Plenum Press, New York

About this chapter

Cite this chapter

Hoshi, Y., Hazeki, O., Tamura, M. (1989). The Oxygen Dependency of the Redox State of Heme and Copper in Cytochrome Oxidase In Vitro . In: Rakusan, K., Biro, G.P., Goldstick, T.K., Turek, Z. (eds) Oxygen Transport to Tissue XI. Advances in Experimental Medicine and Biology, vol 248. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5643-1_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5643-1_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5645-5

  • Online ISBN: 978-1-4684-5643-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics