Abstract
The history of the physiology of extreme altitude is one of the most colorful in the whole area of physiology. Man seems to have a fundamental urge to climb higher and higher, and reaching the summit of Mt. Everest is still often referred to as one of the basic human aspirations. An interesting feature of the history is that physiologists through the years have repeatedly been astonished by some new altitude record but in spite of this have confidently predicted on each occasion that man can go no higher!
Lecture given at the Symposium Banquet, March 27, 1987
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References
Acosta, I. de (1590). Historia natural y moral de las Indias… Seville: luan de Leon, Lib. 3, Cap. 9. [English translation of pertinent pages in: High Altitude Physiology edited by J.B. West, Hutchinson Ross Publishing Company, Stroudsburg, PA, 1981).
Barcroft, J., C.A. Binger, A.V. Bock, J.H. Doggart, H.S. Forbes, G. Harrop, J.C. Meakins, and A.C. Redfield (1923). Observations upon the effect of high altitude on the physiological processes of the human body, carried out in the Peruvian Andes, chiefly at Cerro de Pasco. Phil. Trans. Royal Soc., Ser. B, 211:351–480.
Barcroft, J. (1925). The respiratory functions of the blood. Part I: Lessons from high altitudes. Cambridge, Cambridge University Press.
Bert, P. (1978). La pression barometrique. Masson, Paris. (English translation by M.A. Hitchcock and F.A. Hitchcock. College Book Company, Columbus, OH, 1943).
Brown, T.G. and G. De Beer (1957) The first ascent of Mont Blanc. London, Oxford University Press.
De Sassure, H.B. (1786–1798). Voyages dans les alpes. 4 Vol.: Neuchatel: Louis Fauche-Borel.
Dill, D.B., J.H. Talbott and W.V. Consolazio (1937). Blood as a physic-chemical system XII. Man at high altitudes. J. Biol. Chem. 188:649–666.
Douglas, C.G., J.S. Haldane, Y. Henderson, and E.C. Schneider. (1913). Physiological observations made on Pike’s Peak, Colorado, with special reference to adaptations to low barometric pressures. Phil. Trans. Royal Soc. Ser. B, 203:185–318.
Filippi, F.D. (1912). Karakorum and Western Himalaya. London: Constable.
FitzGerald, M.P. (1913). The changes in the breathing and the blood of various altitudes. Phil. Trans. Royal Soc. London Ser. B, 203:351–371.
Gill, M.G., J.S. Milledge, L.G.C.E. Pugh, and J.B. West (1962). Alveolar gas composition at 21,000 to 25,700 ft. (6400–7830 m). J. Physiol. London 163:373–377.
Glaisher, J., C. Flammarion, E. De Fonvielle and G. Tissandier (1871). Ascents from Wolverhampton. In: Travels in the Air, edited by J. Glaisher. Philadelphia, PA: Lippincott, pp. 50–58.
Haldane, J.S., A.M. Kellas and E.L. Kennaway (1919–1920). Experiments on acclimatization to reduced atmospheric pressure. J. Physiol. London 53:181–206.
Hinchliff, T.W. (1876). Over the sea and far away. London: Longmans, Green.
Hunt, J. (1953). The ascent of Everest. London: Hodder and Stoughton.
Kellas, A.M. (1921). Sur les possibilities de faire I’ascension du Mount Everest. Congres de I’Alpinisme, Monaco, 1920. Comptes Rendus des Seances, Paris 1:451–521.
Keys, A. (1936). The physiology of life at high altitudes: the International High Altitude Expedition to Chile 1935. Sci. Mon. 43:289–312.
Krogh, M. (1915). The diffusion of gases through the lungs of man. J. Physiol. London 49:271–296.
Messner, T. (1979). Everest: expedition to the ultimate. London: Kaye and Ward.
Monge, C. (1948). Acclimatization in the Andes: historical confirmations of “climatic aggression” in the Andean man. Baltimore, Johns Hopkins Press.
Mossor A. (1898). Life of man on the high alps. London: Fisher Unwin.
Pascal, B. (1648). Story of the great experiment on the equilibrium of fluids. (English translation in: High Altitude Physiology edited by J.B. West, Hutchinson Ross Publishing Company, Stroudsburg, PA, 1981).
Pugh, L.G.C.E., M.B. Gill, S. Lahiri, J.S. Milledge, M.P. Ward, and J.B. West (1964). Muscular exercise at great altitudes. J. Appl. Physiol. 19:431–440.
Somervell, T.H. (1925). Note on the composition of alveolar air at extreme heights. J. Physiol. London, 60:282–285.
West, J.B. (1986). Highest inhabitants of the world. Nature 324:517.
West, J.B., P.H. Hackett, K.H. Maret, J.S. Milledge, R.M. Peters, Jr., C.J. Pizzo and R.M. Winslow (1983a). Pulmonary gas exchange on the summit of Mount Everest. J. Appl. Physiol. 55:678–687.
West, J.B., S. Lahiri, K.H. Maret, R.M. Peters, Jr and C.J. Pizzo (1983b). Barometric pressures at extreme altitudes on Mt. Everest: Physiological significance. J. Appl. Physiol. 54:1188–1199.
West, J.B. and P.D. Wagner (1980). Predicted gas exchange on the summit of Mt. Everest. Respir. Physiol. 42:1–16.
Whymper, E. (1891). Travels amongst the great Andes of the equator. London: Murray.
Wylie, A. (1881). Notes on the Western Regions (translated from the Qian Han Shu, Book 96, Part 1). J. Anthrop. Inst. 10:20–73.
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© 1988 Plenum Press, New York
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West, J.B. (1988). High Points in the Physiology of Extreme Altitude. In: Gonzalez, N.C., Fedde, M.R. (eds) Oxygen Transfer from Atmosphere to Tissues. Advances in Experimental Medicine and Biology, vol 227. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5481-9_1
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