Abstract
There is a range of possible functions for individual membrane lipids which encompasses both the general and the highly specific. The outstanding general characteristic of most polar lipids is their ability to form a bilayer with permeability characteristics rather similar to the barrier present in biological membranes. Associated with this fluid lipid bilayer in membranes are transport, enzyme and receptor proteins which require appropriate phospholipid environments for their function: some show little discrimination in their choice of lipids whereas others display rather specific requirements for particular lipids. Many of these protein-lipid interactions, and thus the functions of the proteins, are probably relatively constant over considerable periods. There may, however, be some systems (e.g. certain types of receptors) in which changes in lipid environment and function are produced as a result of physiologically controlled variations in the activities of intrinsic enzymes that act on membrane lipids.
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References
De Pont, J. J. H. H. M., van Prooijen-van Eeden, A. & Bonting, S. L. (1973) Biochim. Biophys. Acta 323, 487–494
Roelefsen, B. & van Deenen, L.L.M. (1973) Eur. J. Biochem. 40, 245–257
Hokin, L.E. & Hexum, T.D. (1972) Arch. Biochem. Biophys. 151, 453–468
Wheeler, K.P. (1975) Biochem. J. 146, 713–727, 723–737, 729–738
Michell, R. H. (1975) Biochim. Biophys. Acta 415, 81–147
Levey, G.S. (1973) Recent Progress in Hormone Research 29, 361–386
Yameshita, K. & Field, J.B. (1973) Biochim. Biophys. Acta 304, 686–692
Tomasi, V., Réthy, A., Trevisiani, A. & Bamabei, O. (1972) in Role of Membranes in Secretory Processes (Bolis, L., Keynes, R. D. & Wilbrandt, W., eds.) pp.88–95, North-Holland Amsterdam
Lefkowitz, R.J. (1975) J. Mol. Cell. Cardiol. 27–37
Vignais, P.M., Vignais, P. V. & Lehninger, A. L. (1964) J. Biol. Chem. 239, 2011–2021
Doery, H. M., Magnusson, B. J., Gulasekharam, J. & Pearson, J. E. (1965) J. Gen. Microbiol. 40, 283–296
Bretscher, M.S. (1973) Science 181, 622–629
Zwaal, R.F.A. (1974) Biochem. Soc. Trans. 2, 821–825
Hokin-Neaverson, M. R. (1974) Biochem. Biophys. Res. Commun. 58, 763–768
Hokin, M.R. (1974) in Secretory Mechanisms of Exocrine Glands (Thorn, N. A. & Pedersen, O. H., eds.) pp.701–712, Munksgaard, Copenhagen
Jones, L.M. & Michell, R.H. (1974) Biochem. J. 142, 583–590
Jones, L.M. & Micheli, R.H. (1975) Biochem. J. 148, 479–483
Jafferji, S.S. & Micheli, R.H. (1975) Biochem. J. submitted
Brindley, D.N. & Bowley, M. (1975) Biochem. J. 148, 461–469
Allan, D. & Micheli, R.H. (1975) Biochem. J. 148, 471–478
Eichberg, J. & Hauser, G. (1974) Biochem. Biophys. Res. Commun. 60, 1460–1467
Brindley, D.N., Allan, D. & Micheli, R.H. (1975) J. Pharm. Pharmacol. 27, 462–464
Dawson, R.M.C. & Hauser, H. (1970) in Calcium and Cellular Function (Cuthbert, A.W., ed.) pp.17–41, Macmillan, London
Allan, D. & Micheli, R.H. (1974) Biochem. J. 142, 599–604
Roufogallis, B.D. (1975) J. Neurochem. 24, 57–61
Wolleman, M. (1974) in Biochemical Basis of Neuropharmacology (Cooper, L., ed.)
Ariens, E.J. & Simonis, A.M. (1967) Ann. N.Y. Acad. Sci. 144, 842–868
Triggle, D.J. (1971) Neurotransmitter-Receptor Interactions, Academic Press, London
Iversen, L.L. (1975) Science 188, 1084–1089
Allan, D. & Micheli, R.H. (1975) Nature in press
Allan, D. & Micheli, R.H. (1975) Biochem. Soc. Trans, in press
Jacob, H.S. & Karnovsky, M.L. (1967) J. Clin. Invest. 46, 173–185
Reed, C.F. (1968) J. Clin. Invest. 47, 2630–2638
Kemp, P., Klein, R.W., Laser, H., Lander, D. & Miller, N. (1975) J. Parasitol in press
Lucy, J.A. & Dingle, J.T. (1964) in Metabolism and Physiological Significance of Lipids (Dawson, R.M.C. & Rhodes, D.N., eds.) pp.384–397, John Wiley, London
Allan, D., liow, M.G., Finean, J.B. & Micheli, R.H. (1975) Biochim. Biophys. Acta in press
Bansbach, M.W., Geison, R.L. & Hokin-Neaverson, M.R. (1974) Biochem. Biophys. Res. Commun. 58, 714–718
Ahkong, Q.F., Fisher, D., Tampion, W. & Lucy, J.A. (1973) Biochem. J. 136, 147–155
De Boer, E. & Loyter, A. (1973) FEES Lett. 15, 325–327
Ahkong, Q.F., Tampion, W. & Lucy, J.A. (1975) Nature 256, 208–209
Rubin, R.P. (1974) Calcium and the Secretory Response, Plenum, New York
Douglas, W.W. (1974) Biochem. Soc. Symp. 39, 1–28
Case, R.M. & Goebell, H., eds. (1975) Stimulus-Secretion Coupling in the Gastrointestinal Tract, MTP Press, Lancaster
Ahkong, Q.F., Fisher, D., Tampion, W. & Lucy, J.A. (1975) Nature 253, 194–195
Williams, D.J., Spanner, S. & Ansell, G.B. (1973) Biochem. Soc. Trans. 1, 466–467
Saito, M. & Kanfer, J. (l975) Arch. Biochem. Biophys. 169, 318–323
Brindley, D.N. (1974) in Intestinal Absorbtion (Smyth, D.H., ed.) pp. 621–671, Plenum Press, New York
Hawthorne, J.N. (1973) in Form and Function of Phospholipids (Ansell, G.B., Hawthorne, J.N. & Dawson, R.M.C., eds.) pp. 423–440, Elsevier, Amsterdam
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Michell, R.H., Allan, D., Finean, J.B. (1976). Significance of Minor Glycerolipids in Membrane Structure and Function. In: Porcellati, G., Amaducci, L., Galli, C. (eds) Function and Metabolism of Phospholipids in the Central and Peripheral Nervous Systems. Advances in Experimental Medicine and Biology, vol 72. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0955-0_1
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DOI: https://doi.org/10.1007/978-1-4684-0955-0_1
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