Abstract
There is no doubt that tissue oxygen concentration is the critical determinant in the energy metabolism of living tissues. The concept of critical oxygen concentration, which was introduced to emphasize this, has been defined as the oxygen concentration at which the respiration rate of the tissue starts to obey first order kinetics rather than zero-order with respect to oxygen. The critical oxygen concentration values reported for isolated mitochondria and tissue show discrepancies. The tissue oxygen gradient can explain the variation between the two.
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© 1988 Plenum Press, New York
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Tamura, M., Hazeki, O., Nioka, S., Chance, B., Smith, D.S. (1988). The Simultaneous Measurements of Tissue Oxygen Concentration and Energy State by Near-Infrared and Nuclear Magnetic Resonance Spectroscopy. In: Mochizuki, M., Honig, C.R., Koyama, T., Goldstick, T.K., Bruley, D.F. (eds) Oxygen Transport to Tissue X. Advances in Experimental Medicine and Biology, vol 222. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9510-6_42
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DOI: https://doi.org/10.1007/978-1-4615-9510-6_42
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