Abstract
The possibility of using hairy root (HR) cultures for producing secondary metabolites on a large scale has recently received a great deal of attention (Flores et al., 1987; Hamill et al., 1987; Rhodes et al, 1987; Scheidegger, 1990; Toivonen, 1993). However, in order to reliably design and scale-up HR culture systems, their growth kinetics must be understood and mathematically modeled (Flint-Wandel et al., 1993; Inomata et al., 1993; Kim et al., 1995; Taya et al., 1989). The shape of the HR batch growth curve has been described using Monod’s equation (Hilton et al., 1988) or the logistic equation (Toivonen et al., 1990), both of which predict the change of total root biomass with time. However, published results (Croes et al., 1989; Yonemitsu et al., 1990; Flores, 1987; Aird et al., 1988) suggest that different HR morphologies result in dissimilar levels of secondary metabolite production. Thus two HR cultures with a similar biomass but different root architectures could have completely different product yields.
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© 1997 Springer Science+Business Media New York
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Berzin, I., Mills, D., Merchuk, J.C. (1997). Morphological Structured Model for Hairy Root Cultures. In: Altman, A., Waisel, Y. (eds) Biology of Root Formation and Development. Basic Life Sciences, vol 65. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5403-5_71
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DOI: https://doi.org/10.1007/978-1-4615-5403-5_71
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