Abstract
The intracellular reduction of oxygen is a natural part of nutrient conversion into energy and results in the production of small amounts of short-lived intermediates of oxygen; superoxide [O2-], singlet oxygen [1O2],hydrogen peroxide [H2O2] and hydroxide radical [OH]1. Naturally occurring enzymatic “scavengers” serve as the primary protection against oxidant injury2. When the production of oxygen intermediates exceeds the scavenging and detoxifying capacity of these enzymes, then lung parenchymal cell injury results3.
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Gordon, R.E., Heller, R.F., Heller, R.F. (1992). Taurine Protection of Lungs in Hamster Models of Oxidant Injury: A Morphologic Time Study of Paraquat and Bleomycin Treatment. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_38
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DOI: https://doi.org/10.1007/978-1-4615-3436-5_38
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