Skip to main content

Spontaneous Ocular Findings and Esthesiometry / Tonometry Measurement in the Göttingen Minipig (Conventional and Microbiologically Defined)

  • Chapter
Ocular Toxicology

Summary

Gross examinations, ocular reflexes, esthesiometry, indirect ophthalmoscopical and biomicroscopical examinations and tonometry were performed in eighteen 6 to 8 week old microbiologically defined and in fourty-nine 2 to 10 month old conventional Göttingen minipigs. Ophthalmological findings often consisted of embryonic remnants (hyaloid artery, pupillary membrane) which seemed to decrease in incidence with time, although this decrease was not confirmed by statistical analysis. The most important findings were either considered to be congenital in origin or of undetermined etiology. The most noteworthy findings were, in decreasing order of incidence, as follows : hyaloid artery remnants (microbiologically defined 83.3 %, conventional 76.5 %), tigroid fundus (microbiologically defined : 72.2 %, conventional : 75.5 %), slight lens opacities (microbiologically defined : 38.9 %, conventional : 41.8 %) and pupillary membrane remnants (microbiologically defined : 33.3 %, conventional : 21.4 %). These findings did not affect the visual capabilities of the pigs.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. L.W. Williams and K.N. Gelatt, Food animal ophthalmology, in : “Textbook of Veterinary Ophthalmology”, K.N. Gelatt, ed., Lea & Febiger, Philadelphia (1981).

    Google Scholar 

  2. D.M. Schiavo and W.E. Field, The incidence of ocular defects in a close colony of Beagle dogs, Lab. Anim. Sci. 24:51 (1976).

    Google Scholar 

  3. R.W. Bellhorn, A survey of ocular findings in 8 to 10 month old Beagles, J. Am. Vet.Med. Assoc. 164:1114(1974).

    PubMed  CAS  Google Scholar 

  4. G. Saint-Macary and C. Berthoux, Ophthalmologic observations in the young Yucatan micropig, Lab. Anim. Sci. 44:334 (1994).

    PubMed  CAS  Google Scholar 

  5. R.W. Bellhorn, A survey of ocular findings in 16 to 24 month old Beagles, J. Am. Vet.Med. Assoc. 162:139 (1973).

    PubMed  CAS  Google Scholar 

  6. L. De Schaepdrijver, P. Simoens, L. Pollet, H. Lauwers, J.J. De Laey, Morphologic and clinical study of the retinal circulation in the miniature pig. B : Fluorescein angiography of the retina, Exp. Eye Res. 54(6):975 (1992).

    Article  PubMed  Google Scholar 

  7. L.F. Rubin, “Atlas of Veterinary Ophthamoscopy”, Lea & Febiger, Philadelphia (1974).

    Google Scholar 

  8. R. Heywood, Juvenile cataracts in the Beagle dog, J. Small. Anim. Pract. 12:171 (1971).

    Article  PubMed  CAS  Google Scholar 

  9. C. Taradach and P. Greaves, Spontaneous lesions in laboratory animals : incidence in relation to age, Crit. Rev. Toxicol. 12:121(1984).

    Article  PubMed  CAS  Google Scholar 

  10. C. Taradach, B. Régnier, J. Perraud, Eye lesions in the Sprague-Dawley rats : type and incidence in rela-tion to age, Lab. Anim. 15:285 (1981).

    Article  PubMed  CAS  Google Scholar 

  11. J.F. Charlin, Etude expérimentale chez le microporc d’un substitut du vitré : le collagène IV humain placentaire, Thèse de Doctoral de Sciences Médicales présentée à la Faculté de Médecine de l’Université de Rouen (1991).

    Google Scholar 

  12. R.W. Bellhorn, Laboratory animal ophthalmology, in : “Textbook of Veterinary Ophthalmology”, K.N. Gelatt, ed., Lea & Febiger, Philadelphia (1981).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer Science+Business Media New York

About this chapter

Cite this chapter

Loget, O. (1995). Spontaneous Ocular Findings and Esthesiometry / Tonometry Measurement in the Göttingen Minipig (Conventional and Microbiologically Defined). In: Weisse, I., Hockwin, O., Green, K., Tripathi, R.C. (eds) Ocular Toxicology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1887-7_41

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1887-7_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5769-8

  • Online ISBN: 978-1-4615-1887-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics