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CNS Integration of Learned Cardiovascular Behavior

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Limbic and Autonomic Nervous Systems Research

Abstract

The intent of the present chapter is to review what is currently known about the involvement of the CNS in learned cardiovascular activity. Although separate, but extensive bodies of literature exist describing conditioning on the one hand and CNS control of the circulatory system on the other, relatively little is known about the CNS integration of learned cardiovascular responses. This is because important information is lacking about (1) cardiovascular dynamics during conditioning, (2) pathways mediating learned responses, and (3) the role of learned cardiovascular respones as biological adjustments.

The research from our laboratory described in this chapter was primarily supported by re­search grants GB-5307, GB-7944, and GB-24713 from the National Science Foundation and by a grant from the Florida Heart Association and its affiliate chapters.

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References

  • Abrahams, V. C., Hilton, S. M., and Zbrozyna, A., 1960, Active vasodilation produced by stimulation of the brain stem: Its significance in the defense reaction, J. Physiol. (London) 154: 491–513.

    CAS  Google Scholar 

  • Abrahams, V. C., Hilton, S. M. and Zbrozyna, A. W., 1964, The role of active muscle vasodilation in the alerting of the defense reaction, J. Physiol. 171: 189–202.

    PubMed  CAS  Google Scholar 

  • Achari, N. K., Downman, C. B., and Weber, W. V., 1968, A cardio-inhibitory pathway in the brain stem of the cat, J. Physiol. 197: 35.

    Google Scholar 

  • Adams, D. B., Baccelli, G., Mancia, G., and Zanchetti, A., 1968, Cardiovascular changes during preparation for fighting behavior in the cat, Nature 220: 1239–1240.

    PubMed  CAS  Google Scholar 

  • Albe-Fessard, D., Oswaldo-Cruz, E. and Rocha-Miranda, C., 1960, Activités évoquées dans le noyau caudé du chat en réponse a des types divers d’afférences. II. Etude microphysiologique, Electroenceph. Clin. Neurophysiol. 12: 405–420.

    PubMed  CAS  Google Scholar 

  • Augenstein, J., 1974, Differential classical conditioning of heart rate and blood pressure in the rhesus monkey. Unpublished Master’s Thesis, Department of Psychology, University of Miami, 1974.

    Google Scholar 

  • Baccelli, G., Guazzi, M., Libretti, A., and Zanchetti, A., 1965, Pressoceptive and chemoceptive aortic reflexes in decorticate and decerebrate cats, Am. J. Physiol. 208: 708–714.

    PubMed  CAS  Google Scholar 

  • Ban, T., 1966, The septo-preoptico-hypothalamic system and its autonomic function, in Progress in brain research: Correlative neurosciences. Part A. Fundamental mechanisms, T. Tokizane & J. P. Schade, eds., Elsevier Publishing Company, Amsterdam.

    Google Scholar 

  • Ban, T., and Shinoda, H., 1961, Experimental studies on the relation between the hypothalamus and conditioned reflex. III. Conditioned response in the variation of the leukocyte count and the blood sugar level, Med. J. Osaka Univ. 11: 439–453.

    Google Scholar 

  • Bernard, C., 1852, De la influence du systéme nerveux grand sympathique sur la chaleur animale, Compt. Rend. 34: 472.

    Google Scholar 

  • Berne, R. M., and Levy, M. N., 1972, Cardiovascular physiology, (2nd ed.) C. V. Mosby, St. Louis.

    Google Scholar 

  • Biscoe, T., and Sampson, S., 1970, Responses of cells in the brain stem of the cat by stimulation of the carotid sinus, glossopharyngeal, aortic, and superior laryngeal nerves, J. Physiol. 209: 341–358.

    PubMed  CAS  Google Scholar 

  • Bloch-Rojas, S., Toro, A., and Pinto-Hamuy, T., 1964, Cardiac vs. somatic-motor conditioned responses in neodecorticated rats, J. Comp. Physiol. Psychol. 58: 233–236.

    PubMed  CAS  Google Scholar 

  • Bolme, P., and Novotny, J., 1969, Conditional reflex activation of the sympathetic cholinergic vasodilator nerves in the dog, Acta Physiol. Scand. 77: 58–67.

    PubMed  CAS  Google Scholar 

  • Brady, J. V., 1967, Emotion and the sensitivity of psychoendocrine systems, in Neurophysiology and emotions, D. C. Glass, ed., Rockefeller University Press, New York.

    Google Scholar 

  • Brady, J., and Nauta, W., 1953, Subcortical mechanisms in emotional behaviors: Affective changes following septal forebrain lesions in the albino rat, J. Comp. Physiol. Psychol. 46: 339–346.

    PubMed  CAS  Google Scholar 

  • Brady, S. V., Kelly, D., and Plumlee, L., 1969, Autonomic and behavioral responses of the rhesus monkey to emotional conditioning, Ann. N.Y. Acad. Sci. 4: 24–31.

    Google Scholar 

  • Brodai, A., 1957, The reticular formation of the brain stem: Anatomical aspects and functional correlations, Oliver and Boyd, Edinburgh.

    Google Scholar 

  • Brown, A. M., 1969, Sympathetic ganglionic transmission and the cardiovascular changes in the defense reaction in the cat, Circulation Res. 24: 843–849.

    PubMed  CAS  Google Scholar 

  • Brust-Carmona, H., and Zarco-Corondao, I., 1971, Instrumental and inhibitory conditioning in cats. II. Effects of paleocortical and caudate nucleus lesion, Boletin del Instituto de Estudies Medicos y Biologicos ( National University, Mexico ), 27: 61–70.

    Google Scholar 

  • Bülbring, E., and Burn, J. H., 1935, The sympathetic vasodilator fibres in the muscles of the cat and dog, J. Physiol. 83: 483–501.

    PubMed  Google Scholar 

  • Bunzl-Federn, E., 1899, Der centrale Ursprung des Nervus Vagus, Monat. Psychiat. Neurol. 5: 1–22.

    Google Scholar 

  • Carlton, P. L., 1962, Some behavioral effects of atropine and methylatropine. Psychol. Rep. 10: 579–582.

    Google Scholar 

  • Chai, C. Y., and Wang, S. C., 1962, Localization of central cardiovascular control mechanism in lower brain stem of the cat, Am. J. Physiol. 202: 25–30.

    PubMed  CAS  Google Scholar 

  • Chorover, S. L., and Gross, C. G., 1963 Caudate nucleus lesions: Behavioral effects in the rat, Science 141: 826–827.

    PubMed  CAS  Google Scholar 

  • Cottle, M. K., 1964, Degeneration studies of primary afferents of IXth and Xth cranial nerves in the cat, J. Comp. Neurol. 122: 329–343.

    PubMed  CAS  Google Scholar 

  • Crill, W. E. and Reis, D. J., 1968, Distribution of carotid sinus and depressor nerves in the cat brain stem, Am. J. Physiol. 214.269–276.

    PubMed  CAS  Google Scholar 

  • Dell, P., 1952, Corelations entre le Systeme vegetatif et le systeme de la vie de relation. Mesencephale, diecephale et cortex cerebral, J. Physiol. (Paris) 44: 471–557.

    CAS  Google Scholar 

  • DiCara, L. V., Braun, J. J., and Pappas, B. A., 1970, Classical conditioning and instrumental learning of cardiac and gastrointestinal responses following removal of neocortex in the rat, J. Comp. Physiol. Psychol. 73: 208–216.

    PubMed  CAS  Google Scholar 

  • Dittmar, C., 1873, Ueber dei Lage des sogennanter Gefässzentrums in der Medulla oblongata, Ber Sachs. Ges. Wiss. Mat. Phys. Kl., 25: 449.

    Google Scholar 

  • Djojosugito, A. M., Folkow, B., Kylstra, P., Lisander, B., and Tuttle, R. S., 1970, Differentiated interaction between the hypothalamic defense reaction and baroreceptor reflexes. I. Effects on heart rate and regional flow resistance. Acta Physiol. Scand. 78: 376–383.

    PubMed  CAS  Google Scholar 

  • Doty, R. W., 1969 Electrical stimulation of the brain in behavioral context, in, P. H. Mussen and M. R. Rosenzweig (eds.), Ann. Rev. Psychol. 20:289–321.

    Google Scholar 

  • Downs, D., Cardozo, C., Schneiderman, N., Yehle, A. L., VanDercar, D. H., and Zwilling, G., 1972, Central effects of atropine upon aversive classical conditioning in rabbits, Psychopharmacol. 23: 318–333.

    Google Scholar 

  • Dreifuss, J. J., and Murphy, J. T., 1968, Convergence of impulses upon single hypothalamic neurons, Brain Res. 8: 167–176.

    PubMed  CAS  Google Scholar 

  • Durkovic, R. G., and Cohen, D. H., 1969, Effects of caudal midbrain lesions and conditioning of heart and respiratory rate responses in the pigeon, J. Comp. Physiol. Psychol. 69: 329–338.

    PubMed  CAS  Google Scholar 

  • Eliasson, S., Folkow, B., Lindgren, P., and Uvnäs, B., 1951, Activation of sympathetic vasodilator nerves to the skeletal muscle in the cat by hypothalamic stimulation, Acta Physiol. Scand. 23: 333–351.

    PubMed  CAS  Google Scholar 

  • Eliasson, S., Lingren, P., and Uvnäs, B., 1952, Representation in the hypothalamus and the motor cortex in the dog of the sympathetic vasodilator outflow to the skeletal muscle, Acta Physiol. Scand. 27: 18–37.

    PubMed  CAS  Google Scholar 

  • Ellen, P., and Powell, E., 1962, Effects of septal lesions on behavior generated by positive reinforcement, Exptl. Neurol. 6: 1–11.

    CAS  Google Scholar 

  • Elster, A. J., VanDercar, D. H., and Schneiderman, N., 1970, Classical conditioning of heart rate discriminations using subcortical electrical stimulations as conditioned and unconditioned stimuli, Physiol. Behay. 5: 503–508.

    CAS  Google Scholar 

  • Euler, U. S. von and Folkow, B., 1958, The effect of stimulation of autonomic areas in the cerebral cortex upon adrenaline and noradrenaline secretion from the adrenal gland of the cat, Acta Physiol. Scand. 42: 313–320.

    Google Scholar 

  • Fang, H. S., and Wang, S. C., 1962, Cardioaccelerator and cardioaugmentor points in the hypothalamus of the dog, Am. J. Physiol. 203: 147–150.

    Google Scholar 

  • Folkow, B., and Uvnäs, B., 1950, Do adrenergic vasodilator nerves exist? Acta Physiol. Scand. 20: 329–337.

    PubMed  CAS  Google Scholar 

  • Folkow, B., Langston, J., Oberg, B., and Prerovsky, I., 1964, Reactions of the different series-coupled vascular sections upon stimulation of the hypothalamic sympatho-inhibitory area, Acta Physiol. Scand. 61: 476–483.

    PubMed  CAS  Google Scholar 

  • Folkow, B., Heymans, C., and Neil, E., 1965, Integrated aspects of cardiovascular regulation, Handbook of Physiology. Circulation, Section 2, Vol. 1, 1787–1824.

    Google Scholar 

  • Francis, J.,Sampson, L.,Gerace, T., and Schneiderman, N., 1973, Cardiovascular responses of rabbits to ESB: Effects of anesthetization, stimulus frequency and pulse train duration, Physiol. Behay. 11:195–203.

    CAS  Google Scholar 

  • Fredericks, A., Moore, J. W., Metcalf, F. U. Schwaber, J. S., and Schneiderman, N., 1974, Selective autonomic blockade of conditioned and unconditioned heart rate changes in rabbits, Pharmacol. Biochem. Behay. 2:in press.

    Google Scholar 

  • Gebber, G. L., and Snyder, D. W., 1970, Hypothalamic control of baroreceptor reflexes. Am. J. Physiol. 218 (1): 124–131.

    PubMed  CAS  Google Scholar 

  • Gellhorn, E., 1957, Autonomic Imbalance and the Hypothalamus, University of Minnesota Press, Minnesota.

    Google Scholar 

  • Gellhorn, E., 1964, Motion and emotion: The role of proprioception in the physiology and pathology of the emotions, Psychol. Rev. 71: 457–472.

    PubMed  CAS  Google Scholar 

  • Giarman, H. J., and Pepeu, G., 1964, The influence of centrally acting cholinolytic drugs on brain acetylcholine levels, Brit. J. Pharmacol. 23: 123–130.

    PubMed  CAS  Google Scholar 

  • Goldfein, A., and Ganong, W. F., 1962, Adrenal medullary and adrenal cortical responses to stimulation of the diencephalon, Am. J. Physiol. 202: 205–211.

    Google Scholar 

  • Green, J. H., 1967, Physiology of baroreceptor function: Mechanism of receptor stimulation, in Baroreceptors and Hypertension, P. Kezall, ed., Pergamon, Oxford.

    Google Scholar 

  • Green, H. D., and Hoff, E. C., 1937, Effects of faradic stimulation of the cerebral cortex on limb and renal volumes in the cat and monkey, Am. J. Physiol. 118: 641.

    Google Scholar 

  • Grinberg-Zylerbaum, J., Prado-Alcala, R., and Brust-Carmona, H., 1973, Correlation of evoked potentials in the caudate nucleus and conditioned motor responses, Physiol. Behay. 10: 1005–1009.

    Google Scholar 

  • Hardy, J. D., 1961, Physiology of temperature regulation, Physiol. Rev. 41: 521–606.

    PubMed  CAS  Google Scholar 

  • Hess, W., 1957, Functional organization of the diencephalon, Grune and Stratton, New York. Hess, W. R., and Brügger, M., 1943, Das subkorticale zentrum der affektiven abwehrreaktion, Hely. Physiol. Acta 1: 33–52.

    Google Scholar 

  • Heymans, L., and Neil, E., 1958, Reflexogenic areas of the cardiovascular system, J. A. Churchill, London.

    Google Scholar 

  • Hilton, S. M., 1963, Inhibition of baroreceptor reflex on hypothalamic stimulation, J. Physiol. (London) 165: 56.

    Google Scholar 

  • Hilton, S. M., and Spyer, K. M., 1969, The hypothalamic depressor area and the baroreceptor reflex, J. Physiol. 200: 107–108.

    Google Scholar 

  • Hilton, S. M., and Spyer, K. M., 1971, Participation of the anterior hypothalamus in the baroreceptor reflex, J. Physiol. 218: 271–293.

    PubMed  CAS  Google Scholar 

  • Hilton, S. M., and Zbrozyna, A. W., 1963, Amygdaloid region for defense reactions and its efficient pathway to the brain stem, J. Physiol. (London) 165: 160–173.

    CAS  Google Scholar 

  • Hirata, Y., 1965, Subcortical projections from the orbital surface of the cat’s brain, Acta Med. Biol. (Miigata), 13: 123–142.

    CAS  Google Scholar 

  • Hockman, H., and Talesnik, J., 1971, Central nervous system modulation of baroreceptor input, Am. J. Physiol. 221 (2): 515–519.

    PubMed  CAS  Google Scholar 

  • Hoff, E. C., and Green, H. D., 1936, Cardiovascular reactions induced by electrical stimulation of the cerebral cortex, Am. J. Physiol. 117: 411–422.

    Google Scholar 

  • Honig, C. R., and Myers, H. A., 1968, Evaluation of possible adrenergic and cholinergic mechanisms in sympathetic vasodilation, Fed. Proc. 27: 1379–1383.

    PubMed  CAS  Google Scholar 

  • Humphreys, P. W., Joels, N., and McAllen, R. M., 1971, Modification of the reflex response to stimulation of carotid sinus baroreceptors during and following stimulation of the hypothalamic defense area in the cat, J. Physiol. 216: 461–482.

    PubMed  CAS  Google Scholar 

  • Kaada, B. R., 1960, Cingulate, posterior orbital, anterior insular, and temporal pole cortex, in Handbook of Physiology. Vol. II, J. Field, H. W. Magoun, and V. E. Hall, eds., Williams and Wilkins, Baltimore.

    Google Scholar 

  • Kaada, B. R., Pribram, K. H., and Epstein, J. A., 1949, Respiratory and vascular responses in monkeys from temporal pole, insula, orbital surface and cingulate gyrus, J. Neurophysiol. 12: 347–356.

    PubMed  CAS  Google Scholar 

  • Klevans, L. R., and Gebber, G. L., 1970, Faciliatory forebrain influence on cardiac component of baroreceptor reflexes, Am. J. Physiol. 219: 1235–1241.

    PubMed  CAS  Google Scholar 

  • Klose, K. J., 1974, Adrenergic and cholinergic blockade of cardiovascular classical conditioning in the rhesus monkey. Unpublished Master’s Thesis, Department of Psychology, University of Miami.

    Google Scholar 

  • Koch, E., 1931, Die Reflextorische Selbsteurung des Kreislaufes, Steinkopf, Leipzig. Kohnstamm, O., 1901, Zur anatomie und physiologie der vagus kerne, Neurol. Zbl. 16: 767–793.

    Google Scholar 

  • Korner, P. I., 1971, Integrative neural cardiovascular control, Physiol. Rev. 51: 312–367.

    PubMed  CAS  Google Scholar 

  • Korner, P. I., Uther, J. B., and White, S. W., 1969, Central nervous integration of the respiratory responses to arterial hypoxia in the rabbit, Circulation Res. 24: 757–776.

    PubMed  CAS  Google Scholar 

  • Kylstra, P. H., and Lisander, B., 1970, Differential interaction between the hypothalamic defense area and baroreceptor reflexes. II. Effects on aortic blood flow as related to work load on the left ventricle, Acta Physiol. Scand. 78: 386–392.

    PubMed  CAS  Google Scholar 

  • Lico, M. C., Hoffman, A., and Covian, M. R., 1968, Autonomic conditioning in the anesthetized rabbit, Physiol. Behay., 3: 673–675.

    Google Scholar 

  • Lindgren, P., and Uvnäs, B., 1953, Vasodilator responses in the skeletal muscles of the dog to electrical stimulation in the oblongata medulla, Acta Physiol. Scand. 29 (Suppl. 137): 105–108.

    Google Scholar 

  • Lindgren, P., and Uvnäs, B., 1954, Postulated vasodilator center in the medulla oblongata, Am. J. Physiol. 6: 68–76.

    Google Scholar 

  • Lindgren, P., Rosen, A., Strandberg, P., and Uvnäs, B., 1956, The sympathetic vasodilator and vasoconstrictor outflow—a cortico-spinal autonomic pathway, J. Comp. Neurol. 105: 95–104.

    PubMed  CAS  Google Scholar 

  • Lafving, B., 1961, Cardiovascular adjustments induced from the rostral cingulate gyrus, Acta Physiol. Scand. 53: (Suppl. 84): I - 82.

    Google Scholar 

  • Magoun, H. W., 1938, Excitability of the hypothalamus after degeneration of corticofugal connections from the frontal lobe, Am. J. Physiol. 112: 530–532.

    Google Scholar 

  • Malmo, R. B., 1965, Classical and instrumental conditioning with septal stimulation as reinforcement, J. Comp. Physiol. Psychol. 60: 1–8.

    PubMed  CAS  Google Scholar 

  • Miller, F., and Bowman, J., 1916, The cardioinhibitory center, Am. J. Physiol. 39: 149–153.

    Google Scholar 

  • Obrist, P. A., and Webb, R. A., 1967, Heart rate during conditioning in dogs. Relationship to somatic-motor activity, Psychophysiol. 4: 7–34.

    CAS  Google Scholar 

  • Obrist, P. A., Sutterer, J. R., and Howard, J. L., 1972, Preparatory cardiac changes: A psychobiological approach, in Classical Conditioning. II. Current Theory and Research, A. H. Black & W. F. Prokasy, eds., Appleton-Century-Crofts, New York, pp. 312–340.

    Google Scholar 

  • Owsjannikow, P., 1871, Die tonischen and reflectorischen centern der gefässnerven, Ber.Sachs. Ges. Wiss. Mat-Phys. Kl. 23:135.

    Google Scholar 

  • Powell, D. A., Goldberg, S. R., Dauth, G. W., Schneiderman, E., and Schneiderman, N., 1972, Adrenergic and cholinergic blockade of cardiovascular responses to subcortical electrical stimulation in unanesthesized rabbits, Physiol. Behay. 8: 927–936.

    CAS  Google Scholar 

  • Ramon y Cajal, 1909, Histologie du systeme nerveux de l’homme et des vertebres, A. Maloine, Paris.

    Google Scholar 

  • Ranson, S. W. and Billingsley, P. R., 1916, Vasomotor reactions from stimulation of the floor of the fourth ventricle, Am. J. Physiol. 41: 85.

    Google Scholar 

  • Reis, D., and Cuenod, N., 1965, Central neural regulation of carotid baroreceptor reflexes in the cat, Am. J. Physiol. 209: 1267–1279.

    PubMed  CAS  Google Scholar 

  • Reis, D. J., and Oliphant, M. C., 1964, Bradycardia and tachycardia following electrical stimulation of the amygdaloid region in the monkey, J. Neurophysiol. 27: 893–912.

    PubMed  CAS  Google Scholar 

  • Rushmer, R. F., 1959, Constancy of stroke volume in ventricular responses to exertion, Am. J. Physiol. 196: 745–750.

    PubMed  CAS  Google Scholar 

  • Rushmer, R. F., 1962, Effects of nerve stimulation and hormones on the heart: The role of the heart in general circulatory regulation, in Handbook of physiology: Circulation, W. F. Hamilton, section ed., Section 2, Volume 1, American Physiology Society Washington, pp. 533–550.

    Google Scholar 

  • Rushmer, R. F., and Smith, O. A., 1959, Cardiac control, Physiol. Rev. 39: 41–68.

    PubMed  CAS  Google Scholar 

  • Schneiderman, N., 1974, The relationship between learned and unlearned cardiovascular responses, in Cardiovascular psychophysiology: Current issues in response mechanisms, biofeedback and methodology, P. A. Obrist, A. H. Black, J. Brenner, and L. V. DiCara, eds., Aldine-Atherton Press.

    Google Scholar 

  • Schneiderman, N., Schwaber, J. S., and Gimpl, M., 1974, ‘Cardiovascular Units’ in anterior and posterolateral hypothalamus, Fed. Proc. 33:430.

    Google Scholar 

  • Schneiderman, N., VanDercar, D. H., Yehle, A. L., Manning, A. A., Golden, T. and Schneiderman, E., 1969, Vagal compensatory adjustment: Relationship to heart rate classical conditioning in rabbits, J. Comp. Physiol. Psychol. 68: 175–183.

    PubMed  CAS  Google Scholar 

  • Schramm, P., and Bignall, K. E., 1971, Central neural pathways mediating active sympathetic muscle vasodilation in cats, Am. J. Physiol. 223: 754–767.

    Google Scholar 

  • Schramm, L. P., Honig, C. R. and Bignall, K. E., 1971 Active muscle vasodilation in primates homologous with sympathetic vasodilation in carnivores, Am. J. Physiol. 221: 768–777.

    PubMed  CAS  Google Scholar 

  • Schwaber, J. S., 1973, Cardioinhibitory units in dorsal motor nucleus and cardiovascular units in hypothalamus and nucleus solitarius of the conscious rabbit. Unpublished doctoral dissertation, Department of Psychology, University of Miami, 1973.

    Google Scholar 

  • Schwaber, J. S., and Schneiderman, N., 1974, Cardiac units in dorsal motor nucleus and nucleus solitarius of the rabbit, Fed. Proc. 33: 429.

    Google Scholar 

  • Sideroff, S., Elster, A. J., and Schneiderman, N., 1972, Cardiovascular classical conditioning in rabbits (Oryctolagus cuniculus) using appetitive or aversive hypothalamic stimulation as the US, J. Comp. Physiol. Psychol. 81: 501–508.

    PubMed  CAS  Google Scholar 

  • Siegel, S., 1972, Conditioning of insulin-induced glycemia, J. Comp. Physiol. Psychol. 78: 233–241.

    PubMed  CAS  Google Scholar 

  • Smith, O. A., Nathan, M. A., and Clarke, N. P., 1968, Central nervous system pathways mediating blood pressure changes, Hypertension 16: 9–22.

    Google Scholar 

  • Subkov, A. A., and Zilov, G. N., 1937, The role of conditioned reflex adaptation in the origin of hyperergic reactions, Bull. Biol. Med. Exptl. 4: 294–296.

    Google Scholar 

  • Uvnäs, B., 1967, Cholinergic vasodilator innervation to skeletal muscles, Circulation Res. 20 (Suppl. 1): 83–90.

    Google Scholar 

  • VanDercar, D. H., Elster, A. S., and Schneiderman, N., 1970, Heart rate classical conditioning in rabbits to hypothalamic or septal US stimulation, J. Comp. Physiol. Psycho/. 72: 145–152.

    CAS  Google Scholar 

  • Wall, P. D., and Davis, G. D., 1951, Three cortical systems affecting autonomic functions, J. Neurophysiol. 14: 507–517.

    PubMed  CAS  Google Scholar 

  • Weber, E. F. W., and Weber, E. H., 1845, Experimenta quibus probatus nervos vagos rotatione machinae galvano-magneticae irritator, motum cordi retardare et adeo intercipare, Ann. Univ. Med. Milano 20: 227–228.

    Google Scholar 

  • Wilson, M. F., Clarke, N. P., Smith, O. A., and Rushmer, R. F., 1961, Interrelation between central and peripheral mechanisms regulating blood pressure, Circulation Res. 9: 491–496.

    PubMed  CAS  Google Scholar 

  • Yehle, A., Dauth, G., and Schneiderman, N., 1967, Correlates of heart-rate classical conditioning in curarized rabbits, J. Comp. Physiol. Psychol. 64: 98–104.

    PubMed  CAS  Google Scholar 

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  1. Department of Psychology, University of Miami, Coral Gables, Florida, USA

    Neil Schneiderman, James Francis, Larry D. Sampson & James S. Schwaber

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Schneiderman, N., Francis, J., Sampson, L.D., Schwaber, J.S. (1974). CNS Integration of Learned Cardiovascular Behavior. In: Limbic and Autonomic Nervous Systems Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4407-0_8

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  • DOI: https://doi.org/10.1007/978-1-4613-4407-0_8

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