Abstract
Photodynamic therapy (PDT) is a relatively new therapeutic modality utilizing a photosensitizing drug, which selectively localizes in tumors and on activation by exposure to light, results in necrosis of the tumor. Like all new therapies directed to cancer, this modality has generated great enthusiasm and initially was heralded as the panacea for this most dreaded of all diseases. Time and experience have tempered this sentiment. However, it does appear to be effective in many situations, although much basic research is required before its exact role in contemporary cancer therapy can be defined. There are two ingredients necessary for this technology to be effective—the photosensitizer and the activating light.
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Gluckman, J.L., Zitsch, R.P. (1990). Photodynamic Therapy in the Management of Head and Neck Cancer. In: Jacobs, C. (eds) Carcinomas of the Head and Neck. Cancer Treatment and Research, vol 52. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1499-8_7
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DOI: https://doi.org/10.1007/978-1-4613-1499-8_7
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