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Definition
KEGG (Kanehisa et al. 2010) (Kyoto Encyclopedia of Genes and Genomes) pathway database is a well-known publicly accessible pathway database. It is one main database of KEGG, which was built in 1995, and is a bioinformatics resource as part of the research projects of the Kanehisa Laboratories in the Bioinformatics Center of Kyoto University and the Human Genome Center of the University of Tokyo. KEGG PATHWAY contains our knowledge curated from scientific literatures on the biological molecular interaction and reaction networks, including protein-protein interaction, protein-DNA binding, protein-ligand interaction, enzyme-mediated biomass reaction, etc. Interactions within one specific biological process or function are drawn manually to pathway maps. By far, there are 365 pathway maps collected from 113,760 references, which are categorized into metabolism, genetic information processing, environmental information processing, cellular processes, organismal systems, human diseases, and drug development.
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Kanehisa M, Goto S, Furumichi M, Tanabe M, Hirakawa M. KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res. 2010;38:D355–D360.
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Qiu, YQ. (2013). KEGG Pathway Database. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_472
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DOI: https://doi.org/10.1007/978-1-4419-9863-7_472
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-9862-0
Online ISBN: 978-1-4419-9863-7
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