Abstract
The Crystal Clear Collaboration has designed and built a family of high resolution small animal PET scanners. These were designed to be used in research laboratories and provide maximum modularity and flexibility. The source code of the data acquisition and reconstruction software is freely available to the users. The design is based on the use of the Hamamatsu R7600-M64 multi-anode photomultiplier tube and an LSO/LuYAP phoswich matrix with one-to-one coupling between the crystals and the photo-detector. A complete system has 80 PMT tubes in four rings with a minimum inner diameter of 137 mm and an axial field of view of 110 mm. The detectors are rotating over 360 degrees so that partially filled ring geometries can be used. This greatly simplifies the combination of PET with other imaging modalities. Single gamma interactions are recorded in list mode format and coincidences are found by software.
Access provided by Autonomous University of Puebla. Download to read the full chapter text
Chapter PDF
Similar content being viewed by others
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
Meyers R., The biological applications of small animal PET imaging, Nucl. Med. Biol. 2001, 28, 585–593
Chatziioannou A.F., Molecular imaging of small animals with dedicated PET tomographs, Eur. J. Med. 2002, 29, 98–114
A PET scanner. Patent WO03/001242A1
W.P. Trower, M.V. Korzhik, A.A. Fedorov et al., Inorganic scintillators and their applications, Ed. P.Dorenbos, Carel W.E.Eijk, Delft University Press, 1995 p.241
CTI Molecular Imaging, Inc., 810 Innovation Drive, Knoxville, TN 37932, USA
U. Heinrichs, U. Pietrzyk, K. Ziemons, Design optimisation of the PMT-ClearPET prototypes based on simulation studies with GEANT3, in 2002 IEEE Nuclear Science Symposium Conference Record, Norfolk, Virginia, USA
Streun, M. et al., Pulse Shape Discrimination of LSO and LuYAP Scintillators for Depth of Interaction Detection in PET in 2002 IEEE Nuclear Science Symposium Conference Record, Norfolk, Virginia, USA
http://www-iphe.unil.ch/~PET/research/gate/
S. Weber, C. Morel, L. Simon, M. Krieguer, M. Rey, B. Grundlich and M. Khodaverdi, Image reconstruction for the ClearPET Neuro, 3rd International Conference on Imaging Technologies in Biomedical Sciences (ITBS 2005), Milos Island, Greece, 25–28. Sep. 2005, submitted for publication to Nucl Instr Meth A
M. Streun, G. Brandenburg, H. Larue, C. Parl, and K. Ziemons, The data Acquisition System of the ClearPET Neuro, a small animal PET scanner, 14th IEEE real time conference, June 2005, Stockholm
M. Rey, J.-M. Vieira, J.-B. Mosset, M. Moulin Sallanon, P. Millet, J.-F. Loude and C. Morel, Measured and simulated specifications of the Lausanne ClearPET scanner demonstrator, Proceedings of the IEEE NSS & MIC conference, PuertoRico, October 2005
D. Christ, A. Hollendung, H. Larue, C. Parl,. M. Streun, S. Weber, K. Ziemons, H. Hailing, “Homogenization of the Multi-Channel PM Gain by inserting light attenuating masks”, Conference Record, 2003 IEEE Nuclear Science Symposium & Medical Imaging Conference, Portland, Oregon, USA, 19–26.11.2003
Photonic Materials, 6 Mallard Way, Strathclyde Business park, Bellshill ML4. Scotland
P.E. Kinahan and J.G. Rogers, “Analytic 3D image reconstruction using all detected events”, IEEE Trans. Nucl. Sci., vol. 36, pp. 964–968, 1989
C. Labbé, K. Thielemans, D. Belluzzo, et al., An object- Oriented Library for 3D PET Reconstruction using Parallel Computing, Proceedings of “Bildverarbeitung fuer die Medizin 1999, Algorithmen-Systeme-Anwendungen”, Informatik aktuell, Springer, Eds. H. Evers, G. Glombitza, T. Lehmann, H.-P. Meinzer (1999) 268–272 [¨.] http://www.hammersmithimanet.com
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer
About this paper
Cite this paper
Auffray, E. et al. (2006). FIRST RESULTS WITH THE CLEARPET SMALL ANIMAL PET SCANNERS. In: Tavernier, S., Gektin, A., Grinyov, B., Moses, W.W. (eds) Radiation Detectors for Medical Applications. NATO Security through Science Series. Springer, Dordrecht . https://doi.org/10.1007/1-4020-5093-3_6
Download citation
DOI: https://doi.org/10.1007/1-4020-5093-3_6
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-5091-6
Online ISBN: 978-1-4020-5093-0
eBook Packages: MedicineMedicine (R0)