Abstract
Expression of mammary-specific genes is under the control of both hormone dependent and independent mechanisms, neither of which may be totally mammary-specific. It seems that a complex interplay of transcription factors may be responsible for mammary expression. Our challenge is to determine whether ELF3 anhion of mammary-specific genes in vivo, and whether they cooperate with other stimuli, such as prolactin. Because the mammary gland is not a static tissue, but can continually undergo cycles of growth, differentiation and function, it will be interesting to examine whether ELF3 and ELF5 operate cooperatively or differentially during these different phases.
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© 2002 Kluwer Academic Publishers
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Thomas, R.S., Ng, A.N., Zhou, J., Tymms, M.J., Doppler, W., Kola, I. (2002). The Elf Group of Ets-Related Transcription Factors. In: Mol, J.A., Clegg, R.A. (eds) Biology of the Mammary Gland. Advances in Experimental Medicine and Biology, vol 480. Springer, Boston, MA. https://doi.org/10.1007/0-306-46832-8_15
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DOI: https://doi.org/10.1007/0-306-46832-8_15
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