On the irrationality of rational design of an HIV vaccine in light of protein intrinsic disorder
Authors
Collection
The elusive appeal of rational design in HIV vaccinology
Curated by Marc H.V. Van Regenmortel, this collection of articles looks into the struggles of finding an efficient vaccine for a human immunodeficiency virus (HIV). This collection puts under question the rational design of an HIV vaccine advocated for more than 15 years and why it turned to be unsuccessful in developing an HIV vaccine. Among others, the philosophical viewpoint of the roles of reductionist approach (reducing biology to chemistry), strong goal-directed intentionality and excessive confidence in the power of rational thinking are to be discussed. Furthermore, the collection is setting up the scene and looking towards other approaches in finding a successful vaccine for an HIV.
Editors
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Marc H V Van Regenmortel
Marc H V Van Regenmortel is an Emeritus Research Director at the CNRS (French National Research Center) in the School of Biotechnology of the University of Strasbourg, France.
Articles (4 in this collection)
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Review of preventative HIV vaccine clinical trials in South Africa
Authors (first, second and last of 5)
