The effect of COVID-19 vaccination status on all-cause mortality in patients hospitalised with COVID-19 in Hungary during the delta wave of the pandemic
Authors (first, second and last of 18)
Collection
Understanding the impact of aging on the susceptibility and response to COVID-19 infection
Guest Editors Drs. Janet M Lord, Elizabeth Sapey and Kylie Belchamber and Editor-in-Chief Dr. Zoltan Ungvari, and the editorial team of GeroScience (Journal of the American Aging Association) invite submission of original research articles, opinion papers and review articles related to research focused on understanding the impact of advancing age and aging processes on the susceptibility and response to COVID-19 infection.
This call-for-papers is aimed at providing a platform for the dissemination of critical novel ideas related to the role that an aged immune system may play in influencing susceptibility to, but also the response to, COVID-19 infection.
• We welcome manuscripts focusing on the kinetics of the immune response to COVID-19 and any similarities to the aged immune phenotype, how this might influence patient outcomes.
• We are also interested in manuscripts concerning the impact that aging of the lung, including senescent cell burden, increased fibrosis risk, play in effecting the rapid decline of the older COVID-19 infected patient.
• Lastly, as a vaccine is currently proposed as the main way out of the current crisis yet immunesenescence results in poor vaccination responses, we are particularly interested in commentaries on how to improve vaccination responses in older adults or alternatives to the vaccine approach.
• Please indicate during the submission process by checking the relevant box that the manuscript is submitted in response to the Call for Papers “Understanding the impact of Aging on the susceptibility and response to COVID-19 infection”.
Editors
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Professor Janet M Lord
Janet Lord is Director of the Institute of Inflammation and Ageing, a multidisciplinary research institute which brings together fundamental scientists and clinicians to translate understanding of the process of inflammation in to new treatments for chronic age-related inflammatory disease and the consequences of major trauma. Her own research focusses on the dysregulation of immunity in old age, in particular the decline in neutrophil function and how this compromises the response to infection and tissue injury. She aims to understand the mechanism involved and to develop novel therapies to improve immunity in older adults.
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Professor Elizabeth Sapey
Professor Liz Sapey is based within the Institute of Inflammation and Ageing and an Honorary Acute Medicine and Respiratory Consultant Physician at the University Hospitals Birmingham NHS Foundation Trust. Her research interests focus on non-communicable inflammatory and infectious diseases associated with ageing, and the impact of inflammation in an ageing host during hospitalization.
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Dr Kylie Belchamber
Dr Belchamber is a respiratory immunologist who studies the function of immune cells in the lungs. Her main focus is the role of macrophages in chronic lung diseases including COPD and alpha-1 antitrypsin deficiency, and she is also interested host-pathogen interactions in the respiratory tract.
Articles (57 in this collection)
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Distinct subsets of anti-pulmonary autoantibodies correlate with disease severity and survival in severe COVID-19 patients
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Effective virus-specific T-cell therapy for high-risk SARS-CoV-2 infections in hematopoietic stem cell transplant recipients: initial case studies and literature review
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Specific nasopharyngeal Corynebacterium strains serve as gatekeepers against SARS-CoV-2 infection
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Results of a systematic review and meta-analysis of early studies on ivermectin in SARS-CoV-2 infection
Authors (first, second and last of 13)
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T-cell cellular stress and reticulocyte signatures, but not loss of naïve T lymphocytes, characterize severe COVID-19 in older adults
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Liver alterations and detection of SARS-CoV-2 RNA and proteins in COVID-19 autopsies
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Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years
Authors (first, second and last of 15)
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Use of convalescent plasma therapy in hospitalised adult patients with non-critical COVID-19: a focus on the elderly from Hungary
Authors (first, second and last of 6)
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The majority of severe COVID-19 patients develop anti-cardiac autoantibodies
Authors (first, second and last of 19)
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A comprehensive analysis of the mutational landscape of the newly emerging Omicron (B.1.1.529) variant and comparison of mutations with VOCs and VOIs
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Different patterns of excess all-cause mortality by age and sex in Hungary during the 2nd and 3rd waves of the COVID-19 pandemic
Authors (first, second and last of 8)
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Continent-wide evolutionary trends of emerging SARS-CoV-2 variants: dynamic profiles from Alpha to Omicron
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SARS-CoV-2 infection in HIV-infected patients: potential role in the high mutational load of the Omicron variant emerging in South Africa
Authors (first, second and last of 4)
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Favipiravir for the treatment of COVID-19 in elderly patients—what do we know after 2 years of COVID-19?
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Persistent viral RNA shedding of SARS-CoV-2 is associated with delirium incidence and six-month mortality in hospitalized COVID-19 patients
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Stringent public health measures during COVID-19 across ischemic stroke care systems: the potential impact of patient perceptions on health care-seeking behaviors
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Humoral immune response after COVID-19 infection or BNT162b2 vaccine among older adults: evolution over time and protective thresholds
Authors (first, second and last of 13)
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Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions
Authors (first, second and last of 5)
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A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor
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Premorbid aspirin use is not associated with lower mortality in older inpatients with SARS-CoV-2 pneumonia
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Modeling of nursing care-associated airborne transmission of SARS-CoV-2 in a real-world hospital setting
Authors (first, second and last of 11)
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The elderly at risk: aldosterone as modulator of the immune response to SARS-CoV-2 infection
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Changes in the SARS-CoV-2 cellular receptor ACE2 levels in cardiovascular patients: a potential biomarker for the stratification of COVID-19 patients
Authors (first, second and last of 24)
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Comparison of antibody and T cell responses elicited by BBIBP-CorV (Sinopharm) and BNT162b2 (Pfizer-BioNTech) vaccines against SARS-CoV-2 in healthy adult humans
Authors (first, second and last of 8)
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A COVID-19-association-dependent categorization of death causes in 100 autopsy cases
Authors (first, second and last of 16)
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Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort—correlation with disease characteristics
Authors (first, second and last of 9)
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Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission
Authors (first, second and last of 8)
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Therapeutic prevention of COVID-19 in elderly: a case–control study
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The hidden interplay between sex and COVID-19 mortality: the role of cardiovascular calcification
Authors (first, second and last of 35)
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Increased procoagulant platelet levels are predictive of death in COVID-19
Authors (first, second and last of 12)
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Results of a hospitalization policy of asymptomatic and pre-symptomatic COVID-19-positive long-term care facility residents in the province of Salzburg—a report from the AGMT COVID-19 Registry
Authors (first, second and last of 11)
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Level of the SARS-CoV-2 receptor ACE2 activity is highly elevated in old-aged patients with aortic stenosis: implications for ACE2 as a biomarker for the severity of COVID-19
Authors (first, second and last of 16)
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Age-associated difference in circulating ACE2, the gateway for SARS-COV-2, in humans: results from the InCHIANTI study
Authors (first, second and last of 6)
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Comparison of clinical characteristics of patients with pandemic SARS-CoV-2-related and community-acquired pneumonias in Hungary – a pilot historical case-control study
Authors (first, second and last of 14)
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Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss
Authors (first, second and last of 6)
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A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin
Authors (first, second and last of 6)
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Companion animals likely do not spread COVID-19 but may get infected themselves
Authors (first, second and last of 9)
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Novel coronavirus epidemic in the Hungarian population, a cross-sectional nationwide survey to support the exit policy in Hungary
Authors (first, second and last of 24)
