Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3
Authors (first, second and last of 9)
Collection
The microbiota–gut–brain axis
Our understanding of the complex and bidirectional signalling relationship between the gastrointestinal tract and the brain is evolving quickly. This relationship, dubbed the microbiota-gut-brain axis, is thought to be involved in many aspects of homeostasis in addition to the pathogenesis of several diseases, ranging from neurological and degenerative conditions to autoimmune diseases.
This cross-journal collection brings together both human and animal studies covering all aspects of the microbiota-gut-brain axis’ role in health and disease, as well as its therapeutic potential. The participating journals, spanning both neuroscience and microbiology, are listed below.
Submissions should be formatted according to individual journal guidelines. Please indicate clearly in the cover letter and as part of the online submission form that the manuscript is to be considered for this collection.
All manuscripts will undergo standard peer review, and must be submitted through the relevant journal's online submission system.
Articles (33 in this collection)
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Surgery-induced gut microbial dysbiosis promotes cognitive impairment via regulation of intestinal function and the metabolite palmitic amide
Authors (first, second and last of 10)
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Microbiota-indole 3-propionic acid-brain axis mediates abnormal synaptic pruning of hippocampal microglia and susceptibility to ASD in IUGR offspring
Authors (first, second and last of 12)
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Gut microbiota and autism spectrum disorders: where do we stand?
Authors (first, second and last of 8)
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Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL
Authors (first, second and last of 17)
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Metagenomics revealed a correlation of gut phageome with autism spectrum disorder
Authors (first, second and last of 5)
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Gut microbes involvement in gastrointestinal cancers through redox regulation
Authors (first, second and last of 5)
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Microbiome and tryptophan metabolomics analysis in adolescent depression: roles of the gut microbiota in the regulation of tryptophan-derived neurotransmitters and behaviors in human and mice
Authors (first, second and last of 14)
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GPR43 stimulation on TCRαβ+ intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity
Authors (first, second and last of 7)
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Effects of dietary supplementation with a carvacrol–cinnamaldehyde–thymol blend on growth performance and intestinal health of nursery pigs
Authors (first, second and last of 10)
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Lactobacillus paracasei L9 affects disease progression in experimental autoimmune neuritis by regulating intestinal flora structure and arginine metabolism
Authors (first, second and last of 5)
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Th17 cells sense microbiome to promote depressive-like behaviors
Authors (first, second and last of 5)
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Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice
Authors (first, second and last of 16)
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Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation
Authors (first, second and last of 5)
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Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease
Authors (first, second and last of 5)
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A prospective investigation into the association between the gut microbiome composition and cognitive performance among healthy young adults
Authors (first, second and last of 5)
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Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia
Authors (first, second and last of 10)
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The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota
Authors (first, second and last of 20)
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Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis
Authors (first, second and last of 16)
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Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omics
Authors (first, second and last of 13)
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Monoassociation with bacterial isolates reveals the role of colonization, community complexity and abundance on locomotor behavior in larval zebrafish
Authors (first, second and last of 11)
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Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse
Authors (first, second and last of 10)
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Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice
Authors (first, second and last of 12)
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Gut microbiota changes in children with autism spectrum disorder: a systematic review
Authors (first, second and last of 9)
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Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice
Authors (first, second and last of 7)
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Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2
Authors (first, second and last of 10)
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Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis
Authors (first, second and last of 14)
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Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis
Authors (first, second and last of 6)
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The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease
Authors (first, second and last of 11)
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Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
Authors (first, second and last of 8)
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The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism
Authors (first, second and last of 5)
