Collection
Liquid Biopsy at the Frontier of Early Detection, Prognosis and Cancer Treatments
- Submission status
- Closed
Liquid biopsies rely upon detection of circulating tumor cells, cell free DNA, RNA, proteins, lipids, and metabolites present in biofluids of patients. These biospecimens can be easily and reproducibly collected for analyses. The rapid advances in sequencing technologies have further helped the development of FDA-approved liquid biopsies companion diagnostic tests used by clinicians.
This special issue published by Molecular Cancer focuses on the clinical aspects of liquid biopsies, in particular validation of novel biomarkers that may serve as signature for non-invasive early detection of cancerous cells, predict patients' risks of disease progression and response to specific therapies.
Articles (19 in this collection)
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Circulating cell-free DNA methylation patterns as non-invasive biomarkers to monitor colorectal cancer treatment efficacy without referencing primary site mutation profiles
Authors (first, second and last of 12)
- Kazuya Yasui
- Toshiaki Toshima
- Takeshi Nagasaka
- Content type: Correspondence
- Open Access
- Published: 03 January 2024
- Article: 1
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Significant CircRNAs in liver cancer stem cell exosomes: mediator of malignant propagation in liver cancer?
Authors (first, second and last of 9)
- Tao Han
- Lujun Chen
- Kai Li
- Content type: Correspondence
- Open Access
- Published: 05 December 2023
- Article: 197
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Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis
Authors (first, second and last of 26)
- Nikolas H. Stoecklein
- Georg Fluegen
- Nuh N. Rahbari
- Content type: Correspondence
- Open Access
- Published: 13 November 2023
- Article: 181
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A circulating cell-free DNA methylation signature for the detection of hepatocellular carcinoma
Authors (first, second and last of 19)
- Si-Cho Kim
- Da-Won Kim
- Young-Joon Kim
- Content type: Correspondence
- Open Access
- Published: 06 October 2023
- Article: 164
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BNIP3 as a potential biomarker for the identification of prognosis and diagnosis in solid tumours
Authors (first, second and last of 17)
- Qin Yu
- Wenhao Fu
- Wei Han
- Content type: Correspondence
- Open Access
- Published: 30 August 2023
- Article: 143
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A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer
Authors (first, second and last of 12)
- Runjie Song
- Peilan Guo
- Xiangdong Li
- Content type: Research
- Open Access
- Published: 05 July 2023
- Article: 104
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Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application
Authors (first, second and last of 7)
- Mingyang Li
- Lei Li
- Xiaonan Chen
- Content type: Review
- Open Access
- Published: 21 February 2023
- Article: 37
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Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis
Authors (first, second and last of 6)
- Yujin Lee
- Jie Ni
- Yong Li
- Content type: Review
- Open Access
- Published: 16 February 2023
- Article: 33
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Emerging roles of tRNA-derived fragments in cancer
Authors (first, second and last of 8)
- Min Fu
- Jianmei Gu
- Xu Zhang
- Content type: Review
- Open Access
- Published: 13 February 2023
- Article: 30
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Letter to the Editor: clinical utility of urine DNA for noninvasive detection and minimal residual disease monitoring in urothelial carcinoma
Authors (first, second and last of 20)
- Kaiwei Yang
- Hailong Hu
- Zhisong He
- Content type: Correspondence
- Open Access
- Published: 04 February 2023
- Article: 25
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A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR
Authors (first, second and last of 17)
- Runjie Song
- Shuoqian Ma
- Xiangdong Li
- Content type: Research
- Open Access
- Published: 23 January 2023
- Article: 16
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Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance
Authors (first, second and last of 6)
- Pavel Stejskal
- Hani Goodarzi
- Mark Jesus M. Magbanua
- Content type: Review
- Open Access
- Published: 21 January 2023
- Article: 15
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A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer
Authors (first, second and last of 12)
- Keisuke Okuno
- Raju Kandimalla
- Ajay Goel
- Content type: Correspondence
- Open Access
- Published: 20 January 2023
- Article: 13
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Clinical application and detection techniques of liquid biopsy in gastric cancer
Authors (first, second and last of 9)
- Shuo Ma
- Meiling Zhou
- Guoqiu Wu
- Content type: Review
- Open Access
- Published: 11 January 2023
- Article: 7
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An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer
Authors (first, second and last of 11)
- Katsuki Miyazaki
- Yuma Wada
- Ajay Goel
- Content type: Correspondence
- Open Access
- Published: 06 January 2023
- Article: 2
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A liquid biopsy signature of circulating exosome-derived mRNAs, miRNAs and lncRNAs predict therapeutic efficacy to neoadjuvant chemotherapy in patients with advanced gastric cancer
Authors (first, second and last of 10)
- Ting Guo
- Xiao-Huan Tang
- Jia-Fu Ji
- Content type: Correspondence
- Open Access
- Published: 12 December 2022
- Article: 216
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BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer
Authors (first, second and last of 9)
- Yanmei Zhang
- Mengdie Fang
- Guang Liang
- Content type: Research
- Open Access
- Published: 02 August 2022
- Article: 158
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Letter to the Editor: An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detection
Authors (first, second and last of 32)
- Hua Bao
- Zheng Wang
- Yang Shao
- Content type: Correspondence
- Open Access
- Published: 11 June 2022
- Article: 129