Collection

Lipids as signaling molecules

Submission status
Closed
Lipids in Health and Disease invites you to submit to this thematic series. While once viewed as a passive mode of energy storage, lipids are now well-understood to serve as integral components of biological membranes and to function as key intracellular and extracellular messengers. Through this role as signaling molecules, both dietary as well as endogenously synthesized and modified lipids modulate key signaling pathways in the cell. Aberrant lipid-mediated signaling has been implicated in a variety of pathologies, including metabolic diseases, chronic inflammation, cancer, and Alzheimer’s disease. The ability of adipose tissue to elaborate a significant number of signaling molecules may lead to its interpretation as an endocrine organ! The lipid molecules for the purpose of this article collection include: saturated and unsaturated fatty acids and their metabolites, sphingolipids and ceramides, endocannabinoids, and other species that are generally regarded as lipids. The collection of papers in this issue addresses the role of lipids as key signaling molecules in health and disease. We would particularly welcome manuscripts that try to bridge the gap between molecular and biochemical aspects of various lipids and their potential clinical applications/implications. Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. In the submission system please make sure the correct collection title is chosen from the additional information tab. Please also indicate clearly in the covering letter that the manuscript is to be considered for the "Lipids as signaling molecules" series.

Articles (9 in this collection)