Abstract
The biocompatibility of endoprostheses used in modern implantology can be increased by impregnating their surface by using liquids with antimicrobial, anti-inflammatory or osteostimulating effect. It is obvious that increasing the amount of impregnated substance will proportionally increase biocompatibility. However, an increase in the total number of pores in the coating is a prerequisite, which will negatively affect the mechanical properties of the coatings. An algorithm for statistical numerical modeling of the porous structure of biocompatible coatings was demonstrated to find the ideal balance between the porosity of the coating, the proportion of impregnated substance, and mechanical characteristics. Experimental studies of porous coatings based on hydroxyapatite on the surface of endoprostheses have proven the applicability of the developed technique. It was possible to achieve a significant increase in the size of pore channels and the proportion of the impregnated substance and, consequently, in biocompatibility without significant loss of the mechanical properties of the coatings.
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This research was performed into framework of financing RFBR grant number 20-07-00637 A.
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Taran, V., Grishina, I., Nikolaev, A., Dodonov, M., Lyasnikova, A. (2022). Increasing Biocompatibility of Endoprostheses by Modeling the Impregnation Process. In: Shamtsyan, M., Pasetti, M., Beskopylny, A. (eds) Robotics, Machinery and Engineering Technology for Precision Agriculture. Smart Innovation, Systems and Technologies, vol 247. Springer, Singapore. https://doi.org/10.1007/978-981-16-3844-2_5
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